I think it is because n3 sometimes creates a few voxels that are very 
bright (or can't handle a very bright voxel that is there), then the 
conform step ends up compressing a lot of voxels into the dark range to 
handle the few bright voxels. I put some stuff in recon-all to try to 
reduce the effect.

doug


On 08/08/2013 11:46 AM, Bruce Fischl wrote:
> maybe try scaling up the orig.mgz then? I never really understood why the
> nu darkens it sometime. Alternatively you could scale up the nu, but you
> will have already lost dynamic range
>
> On Thu, 8 Aug 2013,
> aqure...@nmr.mgh.harvard.edu wrote:
>
>> The 001.mgz actually looks good in this case (in terms of intensity) so
>> I'm not sure if it makes sense to scale it up further. The problem is with
>> the nu.mgz being too dark. I'll try it out though if you think it will
>> also work in this case.
>>
>> - Abid
>>
>>
>> ---------------
>>
>> you could try using --scale <scale factor> to scale the intensities of the
>> 001.mgz up
>>
>> ---------------
>>
>>> Hi Dr. Fischl,
>>>
>>> I had a couple subjects that failed recon-all. Although the error log said
>>> recon-all failed at mri_watershed it looks like the root problem is a
>>> couple steps earlier, because the nu.mgz looks too dark. This was
>>> discussed in a previous thread from 2008.
>>>
>>> http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg07293.html.
>>>
>>> You wrote, "p.s. are the 001.mgz and 002.mgz dark? The orig.mgz? Sometimes
>>> nu_correct can create very dark images, and there are some switches you
>>> can loo through to correct them. Alternatively if it is the 001.mgz,
>>> mri_convert has a scale option you can use."
>>>
>>> On my subject 001.mgz looks good (there was no 002.mgz file). It is only
>>> nu.mgz that looks too dark. It looks like the solution you gave then was
>>> for a problematic 001.mgz file, but from your response it looks as if the
>>> problem was nu.mgz the solution would be different. What are the switches
>>> you can loop through to correct the nu.mgz.
>>>
>>> Thanks,
>>> Abid
>>>
>>>
>>
>>
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>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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