mri_glmfit does not do it. Run mris_preproc. See the tutorial
doug


On 05/31/2013 01:13 PM, Fotiadis, Panagiotis wrote:
> Hey Doug,
>
> Is there any need to co-register the subjects (of the two cohorts) destined 
> for group analysis to the fsaverage space first in order to be able to 
> compare their cortical thickness on the same space, or does mri_glmfit do 
> that?
>
> Thanks again,
> Panos
> ________________________________________
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Fotiadis, Panagiotis
> Sent: Friday, May 31, 2013 12:28 PM
> To: freesurfer@nmr.mgh.harvard.edu
> Subject: Re: [Freesurfer] Group Analysis
>
> Thanks!
> Panos
> ________________________________________
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
> [gr...@nmr.mgh.harvard.edu]
> Sent: Friday, May 31, 2013 12:22 PM
> To: freesurfer@nmr.mgh.harvard.edu
> Subject: Re: [Freesurfer] Group Analysis
>
> yes
> doug
> On 05/31/2013 12:16 PM, Fotiadis, Panagiotis wrote:
>> Hey Doug,
>>
>> Great, but besides the unbalanced numbers in each cohort, the fact that we 
>> have a cross sectional analysis instead of a longitudinal one doesn't matter 
>> right? Would it be correct to say that we still apply the same group 
>> analysis described in the wiki?
>>
>> Thanks,
>> Panos
>> ________________________________________
>> From: freesurfer-boun...@nmr.mgh.harvard.edu 
>> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
>> [gr...@nmr.mgh.harvard.edu]
>> Sent: Friday, May 31, 2013 11:59 AM
>> To: freesurfer@nmr.mgh.harvard.edu
>> Subject: Re: [Freesurfer] Group Analysis
>>
>> Hi Panos, are you asking whether theunbalanced design will leadto one
>> slope being different than another just because the numbers are
>> different? That is not a problem. You can simply follow the instructions
>> on the wiki.
>> doug
>>
>>
>>
>> On 05/31/2013 11:26 AM, Fotiadis, Panagiotis wrote:
>>> Hey Doug,
>>>
>>> Sorry for the overwhelming amount of questions. I wanted to confirm 
>>> something. Suppose you want to do group analysis between two groups say a 
>>> healthy cohort vs a diseased cohort. Each cohort has ~40 and ~30 subjects 
>>> each (different people), and you want to compare how for instance the 
>>> cortical thickness decreases over age in the one group versus the other. Do 
>>> you still set the contrast vector as [0 0 1 -1]  ([intercept 1 intercept 2 
>>> slope 1 slope 2]) and follow the analysis described in 
>>> https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis or do 
>>> you go on a different way since there are different subjects instead of one 
>>> with 40 (or 30) different longitudinal data for each cohort? Don't we need 
>>> to correct the age slopes for the fact that we have 40 (and 30) different 
>>> subjects in each cohort?
>>>
>>> Thanks,
>>> Panos
>>> _______________________________________________
>>> Freesurfer mailing list
>>> Freesurfer@nmr.mgh.harvard.edu
>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>
>>>
>> --
>> Douglas N. Greve, Ph.D.
>> MGH-NMR Center
>> gr...@nmr.mgh.harvard.edu
>> Phone Number: 617-724-2358
>> Fax: 617-726-7422
>>
>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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