Hi all, I am looking for an accurate method of calculating whole brain volume (WBV) from a spreadsheet of FS MRI data. I had previously been using the following method:
1. Sum the following: CSF, lateral ventricles, 3,4,5 ventricles, and the choroid plexus 2. In a second column, sum the following: cortical wm, cerebellar white matter, brain stem, and total gray volume. 3. Whole Brain Volume = 2 - 1 However, this method gave WBV values greater than that of the intracranial volume (ICV) for some participants. Removing brain stem from the equation did not make a big impact. Is there a method to more accurately calculate WBV? Additionally, I am looking for a way to calculate the amount of space in the ICV that is not occupied by the brain (the "gap" volume). I have been using the equation gap = ICV-WBV. Is there, however, a more accurate way to calculate the value of gap, possibly using the sum of the spaces in the brain rather than the difference between ICV and WBV? Sincere thanks, Phil -- Phillip J. Hsu Washington University in St. Louis h...@wustl.edu
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