Hi Ed,

Thanks for that reassurance! Nice to know I didn't do something wrong! I'll 
have a read through of this literature, thank you so much!!! 

Fatima 



-----Original Message-----
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Ed Gronenschild
Sent: 08 July 2011 16:51
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Freesurfer and VBM

Hi Fatima,

Your findings are not surprising. There is plenty of literature
describing problems with the VBM technique. You may read
e.g., Kennedy et al (2009), Neurobiology of Aging, vol. 10,
1657-1676 and references cited herein.

Ed

On 8 Jul 2011, at 15:02, freesurfer-requ...@nmr.mgh.harvard.edu wrote:

>
> Hello,
>
> I'm wondering if anyone could help me out with a question I had. For  
> a study I'm working on, I'm comparing the regional brain volumes in  
> adolescents with and without PTSD. I ran VBM analysis and Freesurfer  
> on my subjects and I found some significant results on VBM (however,  
> only using uncorrected p values) and on Freesurfer, I found no group  
> differences in brain regions. Is there an explanation for that?
>
> If anyone has any thoughts I'd really appreciate it. Thank you kindly!
>
> Fatima

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