Unfortunately, it's slightly slower than my fastest program that uses the library that comes with FPC. I wonder if the dll was compiled with all of the C compiler's optimiaztions turned on.
{$mode objfpc} uses pcre; // from www.renatomancuso.com/software/dpcre/dpcre.htm const patterns : array[1..9] of pchar = ( 'agggtaaa|tttaccct', '[cgt]gggtaaa|tttaccc[acg]', 'a[act]ggtaaa|tttacc[agt]t', 'ag[act]gtaaa|tttac[agt]ct', 'agg[act]taaa|ttta[agt]cct', 'aggg[acg]aaa|ttt[cgt]ccct', 'agggt[cgt]aa|tt[acg]accct', 'agggta[cgt]a|t[acg]taccct', 'agggtaa[cgt]|[acg]ttaccct' ); replacements : array[0..10,0..1] of string[15] = ( ('B', '(c|g|t)'), ('D', '(a|g|t)'), ('H', '(a|c|t)'), ('K', '(g|t)'), ('M', '(a|c)'), ('N', '(a|c|g|t)'), ('R', '(a|g)'), ('S', '(c|t)'), ('V', '(a|c|g)'), ('W', '(a|t)'), ('Y', '(c|t)') ); // Append 2 strings to an ansistring rapidly. Note: the ansistring's // length will be increased by a more than sufficient amount. function append2( var dest: ansistring; len0: longint; s1: pchar; len1: longint; s2: pchar; len2: longint): longint; inline; const quantum = 599000; var newlength: longint; begin newlength := len0 + len1 + len2; // Since setlength() is somewhat costly, we'll do it less // often than you would think. if length( dest ) < newlength then setlength( dest, newlength + quantum ); move( s1^, dest[len0 + 1], len1 ); move( s2^, dest[len0 + 1 + len1], len2 ); exit( newlength ); end; procedure replace_matches( const str: ansistring; var dest: ansistring ); var rx : iregex; capture: imatch; start, index, truelength, i : longint; target, repl, found: string[255]; begin target := '['; for i := 0 to high(replacements) do target += replacements[i,0]; target += ']'; rx := regexCreate( target ); dest := ''; truelength := 0; start := 0; repeat capture := rx.match( str, start ); if not capture.success then break; index := capture.groups[0].index; found := str[ index + 1 ]; repl := replacements[ pos(found,target)-2, 1 ]; truelength := append2( dest, truelength, @str[start+1], index-start, @repl[1], length(repl) ); start := index + 1; until false; setlength( dest, truelength ); dest := dest + Copy( str, start+1, length(str) - start + 1); end; function count_matches( const needle, haystack: ansistring ):longint; var rx : iregex; capture: imatch; where: longint; begin rx := regexCreate( needle ); result := 0; where := 0; repeat capture := rx.match( haystack, where ); if not capture.success then break; inc( result ); where := capture.groups[0].index + capture.groups[0].length; until false; end; var pattern : pchar; sequence, new_seq : ansiString; line: string[255]; i, count, init_length, clean_length: longint; inbuf : array[1..64*1024] of char; begin settextbuf(input,inbuf); sequence := ''; init_length := 0; while not eof do begin readln( line ); init_length += length( line ) + 1; if line[1] <> '>' then sequence := sequence + line; end; clean_length := length(sequence); for i := low(patterns) to high(patterns) do begin pattern := patterns[i]; count := count_matches( pattern, sequence ); writeln( pattern, ' ', count); end; replace_matches(sequence, new_seq); writeln; writeln( init_length ); writeln( clean_length ); writeln( length(new_seq) ); end. __________________________________________________ Do You Yahoo!? Tired of spam? Yahoo! Mail has the best spam protection around http://mail.yahoo.com _______________________________________________ fpc-pascal maillist - fpc-pascal@lists.freepascal.org http://lists.freepascal.org/mailman/listinfo/fpc-pascal