On Fri, Aug 7, 2020 at 2:46 PM John Clark <[email protected]> wrote:
> On Fri, Aug 7, 2020 at 2:51 PM Jason Resch <[email protected]> wrote: > > > The scientific consensus is based on scientific studies, is it not? >> > > Yes. > > *> Every single study <https://c19study.com/> (dozens of them) that >> investigated early and prophylactic use of HCQ showed a benefit, without >> exception.* >> > > A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for > Covid-19 <https://www.nejm.org/doi/full/10.1056/NEJMoa2016638> > > *> So then, what is the scientific consensus on early/prophylactic use?* > > > *"CONCLUSIONS: After high-risk or moderate-risk exposure to Covid-19, > hydroxychloroquine did not prevent illness compatible with Covid-19 or > confirmed infection when used as postexposure prophylaxis within 4 days > after exposure. [...] Side effects were more common with hydroxychloroquine > than with placebo"* > > The *CONCLUSIONS* don't align with what the *RESULTS* section said right above. "We enrolled 821 asymptomatic participants. Overall, 87.6% of the participants (719 of 821) reported a high-risk exposure to a confirmed Covid-19 contact. The incidence of new illness compatible with Covid-19 did not differ significantly between participants receiving hydroxychloroquine (49 of 414 [11.8%]) and those receiving placebo (58 of 407 [14.3%]); the absolute difference was −2.4 percentage points (95% confidence interval, −7.0 to 2.2; P=0.35). Side effects were more common with hydroxychloroquine than with placebo (40.1% vs. 16.8%), but no serious adverse reactions were reported." So infection rates in the control group were 14.3% and in the group receiving HCQ were 11.8%. That's an absolute risk reduction of (14.3-11.8)/14.3 = 17.5%. Moreover, the claim is that HCQ reduces severity of the symptoms, leading to less hospitalization and death, not that it grants immunity from contracting it. The test did not find a negative result, it failed to reach statistical significance because their sample size was too small. See more information about that study here: https://c19study.com/boulware.html Jason -- You received this message because you are subscribed to the Google Groups "Everything List" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To view this discussion on the web visit https://groups.google.com/d/msgid/everything-list/CA%2BBCJUgZqodLXtJpG9AZsoAQQKEGoe1hSY97WAvufdTsD6b%2BUQ%40mail.gmail.com.
