On Thu, Apr 24, 2025 at 6:23 AM 'Cosmin Visan' via Everything List <
[email protected]> wrote:

*> Of course Cosmin Visan's brain doesn't exist *


*I never thought I'd say this but, I agree with Cosmin Visan. *

*John K Clark    See what's on my new list at  Extropolis
<https://groups.google.com/g/extropolis>*
vca


>> On Tuesday, 22 April 2025 at 22:26:17 UTC+3 John Clark wrote:
>>>
>>>> *It has long been known that learning and long-term memories are
>>>> produced by the strengthening and weakening of synaptic connections between
>>>> neurons, called "neuron plasticity", but it has not been clear what
>>>> determines which synapses are modified during learning in memory formation
>>>> and by how much. Two articles in the April 18, 2025 issue of the Journal
>>>> Science cast some light on that mystery: *
>>>>
>>>> *Dendritic arbors structure memories*
>>>> <https://www.science.org/doi/10.1126/science.adx0640>
>>>>
>>>> *Distinct synaptic plasticity rules operate across dendritic
>>>> compartments in vivo during learning*
>>>> <https://www.science.org/doi/10.1126/science.ads4706>
>>>>
>>>> *It turns out which of the many dendrites that a neuron that receives
>>>> an input signal is important in choosing what rules that neuron will
>>>> follow, which in turn determines whether the entire neuron will fire or
>>>> not. Some neurons pay more attention to signals from nearby neurons while
>>>> others find distant neurons to be more interesting. And synapses in
>>>> different parts of the brain have different rules. This increases the
>>>> information storage capacity of a single neuron.*
>>>>
>>>> *William J Wright, the lead author of the paper says: *
>>>>
>>>> *“When people talk about synaptic plasticity, it’s typically regarded
>>>> as uniform within the brain, our research provides a clearer understanding
>>>> of how synapses are being modified during learning, with potentially
>>>> important health implications since many diseases in the brain involve some
>>>> form of synaptic dysfunction.”*
>>>>
>>>> * Takaki Komiyama another author of the paper says: *
>>>>
>>>> *“This discovery fundamentally changes the way we understand how the
>>>> brain solves the credit assignment problem, with the concept that
>>>> individual neurons perform distinct computations in parallel in different
>>>> subcellular compartments.”*
>>>>
>>>> *I wouldn't be surprised if AI scientists take note of this and make a
>>>> neural net in a similar way to see if that improves performance, but just
>>>> because nature produces intelligence in a certain way is no guarantee that
>>>> is the best way to do it. *
>>>>
>>>>

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