Asking for items 600-615 from a threaded list, sorted by something, can be an 
expensive operation, especially if you just asked for items 585-600 a moment 
ago?

Can be, but is it? :) Dovecot attempts to cache/index stuff as well. Normally 
there shouldn't be a need for extra caching layer except in cases of higher 
network latency.

that is my point. and - esp. with webmail, i see no point to run such service in different place than dovecot server runs. Best - same server. Maybe - other server connected with fast LAN.

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