> I don't think you can controll it through my.cnf.
>  You'll have to edit the init script to add the LD_PRELOAD environment
> variable when mysqld/mariadbd loads.

If instead of the systemd the wrapper script (mariadbd-safe) is used then 
theoretically/technically you can: 
https://mariadb.com/docs/server/server-management/install-and-upgrade-mariadb/compiling-mariadb-from-source/compiling-mariadb-with-extra-modulesoptions/using-mariadb-with-tcmalloc-or-jemalloc#starting-mariadbd-safe-with-an-alternative-to-malloc
  

rr


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