Ok, long story short, I was able to install and run gnuradio on macOS. In MacPorts, I uninstalled gnuradio and all dependencies, then reinstalled gnuradio. When I ran gnuradio-companion in terminal, I got an error messages similar to those described in:
https://github.com/gnuradio/gnuradio/issues/3893 So, I uninstalled gnuradio again and reinstalled with the variants shown in the GitHub link above: sudo port install gnuradio -x11 +no_x11 +quartz It’s a longer install— more things are built from source (including gnuradio itself), but, that worked. When I run gnuradio-companion I still get a message: No such schema “org.gnome.desktop.interface” but that doesn’t seem to matter. I also get some deprecation warnings when a flowgraph is run. The blocks and text in the gnuradio-companion flowgraphs are extremely small. I’ll have to see if that can be fixed. In the mean time, gnuradio does run faster on this newer Mac!