Dear all, Just wanted to share a preprint describing the generation of a minimalistic plasmid which got 56% size reduction from elimination of "useless bloat" DNA code, while actually gaining additional functionality (more restriction enzyme cloning sites).
https://www.preprints.org/manuscript/201807.0287/v2 The preprint paper is not really hypothesis-driven science as such and more a description of the generation of a very useful tool, so I do not think I will try to make it published "for real".
