Hi Tim,
Lol rbay, I remembered your talking about this and wondered if you would bite!
Cheers!
Sean

-----Original Message-----
From: Miller, Timothy [mailto:timothy.mil...@childrens.harvard.edu] 
Sent: Wednesday, February 15, 2017 2:26 PM
To: dev@ctakes.apache.org
Subject: Re: Phenotype-specific entities [SUSPICIOUS] [SUSPICIOUS] [SUSPICIOUS]

Lol was just about to send this:
https://urldefense.proofpoint.com/v2/url?u=https-3A__github.com_tmills_umls-2Dgraph-2Dapi&d=DwIFAw&c=qS4goWBT7poplM69zy_3xhKwEW14JZMSdioCoppxeFU&r=fs67GvlGZstTpyIisCYNYmQCP6r0bcpKGd4f7d4gTao&m=qRZhkS_DX1IuuFC4Yk5QiDUt-vqEIeGD7jH-6f_bOFg&s=WhgfFeTaNOm4ZqVuro3orZC12EMUcVlawyJy6RSpj9w&e=
 

It points at your umls META directory, reads in the ctakes list of TUIs, and 
builds a neo4j graph database with all the ISA links, and has a simple API for 
getting parent/child CUIs.
I used it for coreference.
Tim

________________________________________
From: Finan, Sean <sean.fi...@childrens.harvard.edu>
Sent: Wednesday, February 15, 2017 2:23 PM
To: dev@ctakes.apache.org
Subject: RE: Phenotype-specific entities [SUSPICIOUS] [SUSPICIOUS]

The dictionary gui doesn't walk the ontology.  There are umls tables that list 
relations, wherein things like "isa" (is a) relations may satisfy a hypernym 
requirement.  If you have the umls rrf files look at mrrel.rrf.  The structure 
is basically concept1|..| concept2|..|relationtype|..   See section 3.3.9: 
https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_books_NBK9685_&d=DwIFAg&c=qS4goWBT7poplM69zy_3xhKwEW14JZMSdioCoppxeFU&r=Heup-IbsIg9Q1TPOylpP9FE4GTK-OqdTDRRNQXipowRLRjx0ibQrHEo8uYx6674h&m=agwhlSpSUQ0H6VeJpnACDGcka2fVYSy3HaITKaJN9S8&s=aODQU20_0mAv1i_izwB3RZGOBB0U0ZucFkByxovUJJc&e=

If anybody has made anything that parses/uses umls relations and can be used by 
ctakes, please contribute!  Something like a simple traversable umls graphdb 
would be a great addition ...  Even if it is incomplete or rough, it could be a 
valuable seed for a new effort.

Sean

-----Original Message-----
From: Savova, Guergana [mailto:guergana.sav...@childrens.harvard.edu]
Sent: Wednesday, February 15, 2017 1:54 PM
To: dev@ctakes.apache.org
Subject: RE: Phenotype-specific entities [SUSPICIOUS]

I don't believe there is a tool for walking the UMLS ontology, Dima. But Sean 
should confirm that his dictionary building tool does not have that 
functionality.

I think you can use the UMLS tables to get that information. It has been quite 
a while I have used these tables, but I remember I was able to get that 
information from them...

Sean,
Does your dictionary building tool implement ontology walking?

--Guergana

-----Original Message-----
From: Dligach, Dmitriy [mailto:ddlig...@luc.edu]
Sent: Wednesday, February 15, 2017 1:50 PM
To: dev@ctakes.apache.org
Subject: Re: Phenotype-specific entities

Guergana, thank you.

Is there anything in cTAKES now for walking the UMLS ontology (e.g. for finding 
hypernyms, synonyms, etc.)?

Dima



> On Feb 15, 2017, at 12:45, Savova, Guergana 
> <guergana.sav...@childrens.harvard.edu> wrote:
>
> Hi Erin,
> Yes, creating your customized dictionary is the way to go. You can prune by 
> semantic types of interest and then remove branches that are not relevant to 
> your specific phenotype. I am not aware of cTAKES implementing such a tool 
> for a very customized dictionary.
>
> You can also start with  a few terms that you know are relevant to your 
> phenotype and then find their synonyms in the UMLS. Then, you can further 
> walk a specific ontology and take siblings, parents if you think they are 
> relevant.
>
> Then, there is the whole field of using word embeddings to find 
> synonyms/related terms from unlabeled data  if you want to become really 
> fancy :-) At this point, cTAKES does not implement any deep learning 
> algorithms, in the future we are planning to release a bridge to KERAS.
>
> I hope this makes sense.
>
> --
> Guergana Savova, PhD, FACMI
> Associate Professor
> PI Natural Language Processing Lab
> Boston Children's Hospital and Harvard Medical School
> 300 Longwood Avenue
> Mailstop: BCH3092
> Enders 144.1
> Boston, MA 02115
> Tel: (617) 919-2972
> Fax: (617) 730-0817
> guergana.sav...@childrens.harvard.edu
> Harvard Scholar: 
> https://urldefense.proofpoint.com/v2/url?u=http-3A__scholar.harvard.edu_guergana-5Fk-5Fsavova_biocv&d=DwIFAw&c=qS4goWBT7poplM69zy_3xhKwEW14JZMSdioCoppxeFU&r=SeLHlpmrGNnJ9mI2WCgf_wwQk9zL4aIrVmfBoSi-j0kfEcrO4yRGmRCJNAr-rCmP&m=EMsbVKH4fuTPUXGVRWfjw4vqV3ifyKdh-3K3OLUIogI&s=oAz3p_diNUmQdKL6UIfE9Vsnj1T4H5xq6CIof1jXisU&e=
> ctakes.apache.org
> thyme.healthnlp.org
> cancer.healthnlp.org
> share.healthnlp.org
>
>
> -----Original Message-----
> From: Erin Nicole Gustafson [mailto:erin.gustaf...@northwestern.edu]
> Sent: Wednesday, February 15, 2017 1:38 PM
> To: dev@ctakes.apache.org
> Subject: Phenotype-specific entities
>
> Hi all,
>
> I would like to be able to only identify entities that are relevant for some 
> specific phenotype. One step towards achieving this would be to build a 
> custom dictionary with a limited set of semantic types. However, this is not 
> quite specific enough to only identify mentions related to one disease while 
> ignoring those related to some other disease, for example.
>
> Does cTAKES currently have a way to do this sort of filtering? Or, has anyone 
> developed their own tools that they'd be willing to share?
>
> Thanks,
> Erin

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