I just upgraded to Mavericks and ran into a number of issues. Hope this helps 
others.
 - MySQL needed to be reinstalled
 - Eclipse wouldn’t start because it wanted a Java 6 runtime. I fixed the issue 
by downloading the latest JDK7 from Oracle (64-bit) and following this SO: 
http://stackoverflow.com/a/19737307)
 - pip had to be reinstalled (easy_install pip)
 - cloudmonkey had to be reinstalled (sudo pip install cloudmonkey)
 - maven had to be reinstalled (brew install maven)

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