I have the same issue on a new Asus Zenbook prime UX31A-R4003P. For me, it seems that the problem appears when I use VirtualBox. Suddenly, the mouse click does not work anymore on the laptop screen but it works on my external screen (HDMI one).
If I click <<Alt>> key as said by Andrey Sidorov, this solves the problem. -- You received this bug notification because you are a member of Desktop Packages, which is subscribed to xserver-xorg-input-synaptics in Ubuntu. https://bugs.launchpad.net/bugs/1077805 Title: left click stops working after a while Status in “xserver-xorg-input-synaptics” package in Ubuntu: Confirmed Bug description: I did a clean install of Quantal a few days ago. I have a five year old Lenovo N100 3000 laptop. The install went smoothly and everything worked fine until later this evening. This started happening when playing scrabble on Facebook. The clicks would stop working. After a restart, it would work normally, but after an hour or so, it would stop working. I know this isn't a hardware issue, because I plugged in a USB mouse as well, and it had the same problem when the left click (and even right click on one occasion) wasn't working on my trackpad (tapping on the trackpad for left click stopped working too). How do I find out what's causing this, and more importantly, how do I fix it? P.S. I'll add an update in case it works fine if I don't use the Scrabble app. To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/xserver-xorg-input-synaptics/+bug/1077805/+subscriptions -- Mailing list: https://launchpad.net/~desktop-packages Post to : desktop-packages@lists.launchpad.net Unsubscribe : https://launchpad.net/~desktop-packages More help : https://help.launchpad.net/ListHelp