It looks like you're using Xorg fractional scaling, so yes that will take the texture requirements past the limit supported by the GPU if you do it across multiple 4K monitors. Some parts of the desktop will cope and other parts (GTK) might not cope.
To confirm this, please run: xrandr --verbose > xrandr.txt and attach the resulting text file here. Possible workarounds (you only need one): * Only use integer scaling * Only use Wayland sessions * Use fewer monitors ** Package changed: gnome-shell (Ubuntu) => gtk+3.0 (Ubuntu) ** Package changed: gtk+3.0 (Ubuntu) => ubuntu ** Package changed: ubuntu => nvidia-graphics-drivers-525 (Ubuntu) ** Package changed: gnome-shell-extension-desktop-icons-ng (Ubuntu) => gtk+3.0 (Ubuntu) ** Tags added: xrandr-scaling -- You received this bug notification because you are a member of Ubuntu Desktop Bugs, which is subscribed to gnome-shell in Ubuntu. https://bugs.launchpad.net/bugs/2004533 Title: very unstable desktop, icons vanish, cannot control windows, cannot resize or scale multi monitors easily. To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/gtk+3.0/+bug/2004533/+subscriptions -- desktop-bugs mailing list desktop-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/desktop-bugs