Package: wnpp Severity: wishlist
* Package name : mssstest Version : 2.0 Upstream Author : Shaun Seaman and Richard Roxburgh <[EMAIL PROTECTED]> * URL : http://www-gene.cimr.cam.ac.uk/MSgenetics/GAMES/MSSS * License : public domain but must not be sold -> non-free Description : Normalisation of EDSS disease score of patients with Multiple Sclerosis Suppose one is interested in determining whether the genotype at some locus of interest affects the rate of progression of disease of people with Multiple Sclerosis (MS). One method would be to calculate the mean EDSS score in patients with each of the genotypes and test whether they are significantly different. However, this approach is inefficient if patients have their EDSS assessed at different durations of disease, as patients who have had MS longer typically have higher EDSS scores regardless of their genotype. By adjusting for duration, a more powerful test can be developed. MSSStest is a program for implementing the method described in the article The Multiple Sclerosis Severity Score. R. Roxburgh S. Seaman et al. (2004), accepted for publication by Neurology. It calculates MSSS scores and uses these scores to test for differences between disease progression rates in different groups defined by genotype at some locus. A brief description of the method is given below. The application of this predictor is technically not constrained to Multiple Sclerosis which justifies the presentation as a Debian package. I have created a package and hope for a sponsor - which is of course a bit tricky for non-DFSG-compliant software. Kind regards Steffen -- System Information: Debian Release: 3.1 APT prefers unstable APT policy: (500, 'unstable'), (500, 'testing') Architecture: i386 (i686) Kernel: Linux 2.4.20 Locale: LANG=C, LC_CTYPE=C
