Package: wnpp Severity: wishlist Owner: Andreas Tille <ti...@debian.org>
* Package name : minimap2 Version : 2.12 Upstream Author : Copyright: © 2017-2018 Broad Institute <hen...@broadinstitute.org> * URL : https://github.com/lh3/minimap2 * License : MIT Programming Lang: C Description : versatile pairwise aligner for genomic and spliced nucleotide sequences Minimap2 is a versatile sequence alignment program that aligns DNA or mRNA sequences against a large reference database. Typical use cases include: (1) mapping PacBio or Oxford Nanopore genomic reads to the human genome; (2) finding overlaps between long reads with error rate up to ~15%; (3) splice-aware alignment of PacBio Iso-Seq or Nanopore cDNA or Direct RNA reads against a reference genome; (4) aligning Illumina single- or paired-end reads; (5) assembly-to-assembly alignment; (6) full- genome alignment between two closely related species with divergence below ~15%. . For ~10kb noisy reads sequences, minimap2 is tens of times faster than mainstream long-read mappers such as BLASR, BWA-MEM, NGMLR and GMAP. It is more accurate on simulated long reads and produces biologically meaningful alignment ready for downstream analyses. For >100bp Illumina short reads, minimap2 is three times as fast as BWA-MEM and Bowtie2, and as accurate on simulated data. Detailed evaluations are available from the minimap2 paper or the preprint. Remark: This package is maintained by Debian Med Packaging Team at https://salsa.debian.org/med-team/minimap2
