system: amd64 desktop, debian 12, xfce, NEC MultiSync EA192M monitor
I don't know precisely how to describe the problem, other than "detachment". About every week or so, when using the rodent, the entire screen -- borders and all -- moves with respect to the monitorscreen as I move the mouse.
The only recovery method I have discovered is to reboot. My hands and finders no longer are working well, so I likely clicked on something or pressed a key to cause the problem. RLH