I guess so

since FHS says

/bin contains commands that may be used by both the system administrator
and by users, but which are required when no other filesystems are
mounted (e.g. in single user mode)

I guess nothing warrants hmmer to run in single user mode

On Thu, 26 Aug 2010, Felipe Figueiredo wrote:
> I just noted that binaries in hmmer 3.0-1 are located in /bin instead
> of /usr/bin. Is this a bug?

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