Actually, MySQL replication has tendencies to die for us for weird reasons that we're still trying to track down. In our case, it is almost exclusively a case where a field is added to a table on the master, and the change does not propagate to the slave. But, we also have one database that simply refuses to replicate - its inserts/updates don't even make it to the binlog, even though there is nothing I can find in the configuration that would exclude it.
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