http://www.nytimes.com/2001/10/17/national/17WEAP.html?pagewanted=print

Sign of Escalating ThreatBy STEPHEN ENGELBERG and JUDITH MILLERNews AnalysisThe 
discovery of what government officials say is high-grade anthraxin a letter mailed to 
Congress is the most worrisome development yetin a series of bioterrorist attacks that 
has already rattled thenation.The officials and weapons experts said yesterday that it 
suggestedthat somewhere, someone has access to the sort of germ weapons capableof 
inflicting huge casualties.So far, the officials said, the attacker or attackers have 
used arudimentary delivery system: the mail. Their intent and capabilitiesremain 
unknown, as does the amount of anthrax available to them. Butwhat worries the 
officials in Washington is the possibility that anadversary with even a small quantity 
could easily find much moreeffective means of spreading the disease.Until yesterday's 
preliminary analysis of the letter received by TomDaschle, the Senate majority leader, 
the spate of anthrax-lacedenvelopes stirred considerable anxie!
ty!
 but posed a limited threat.Some experts assumed that the anthrax being sent around 
the countrywas crudely made, composed mostly of large particles that fell to theground 
and thus endangered primarily those in the immediate area.What government officials 
say arrived in Senator Daschle's office wassignificantly more threatening. Following 
the use of anthrax inFlorida, it suggests that for the first time in history 
asophisticated form of anthrax has been developed and used as a weaponin warfare or 
bioterrorism.The key to understanding the danger, experts said, is in the size ofthe 
particles. The anthrax sent to Mr. Daschle, government officialssaid, was finely 
milled so that it would float a considerable distanceon the smallest of air 
currents.Producing germs that could be spread as a mist had been the maintechnical 
challenge facing germ warriors throughout the 20th century.Anthrax is what the Nobel 
laureate Joshua Lederberg calls a"professional pathogen," a hardy germ that co!
ul!
d wreak havoc ifinhaled. The trick was turning it into an aerosol that lingers.Decades 
ago, Soviet and American scientists separately devised methodsto dry and grind anthrax 
into the tiny particles — five microns orless — that could easily enter the nostrils 
and lodge in the lungs.Experts say an adversary armed with anthrax in this form would 
have ahost of possible targets for mass terrorism. Experiments by the UnitedStates in 
the 1960's showed that anthrax released in the New York Citysubway could spread widely 
underground, infecting large numbers ofpeople. Federal officials used a benign germ 
related to anthrax todemonstrate the possible effects.An enemy with large quantities 
of high-grade anthrax could mount acredible attack on a city or large office building. 
Dried anthraxcould be spread using a crop-duster or small airplane equipped withthe 
appropriate nozzles. Buildings are an easier target and could becontaminated with a 
much smaller amount of anthrax pumped through a!
ga!
rden spray bottle, experts say.Victims of an anthrax attack can be easily treated with 
antibiotics,but that requires that public health officials recognize the germ hasbeen 
dispersed at a particular location. Experts say that detectionequipment is far from 
reliable, which means the first signs could comewhen people show up in the emergency 
room with flulike symptoms.Anthrax was one of the most important weapons in both the 
SovietUnion's and the United States' germ weapons arsenals.Officials from both 
countries say they never used germ weapons, thoughKen Alibek, a prominent defector 
from the Soviet germ warfare program,maintains that Moscow may have used germs as 
weapons against Germanyand in Afghanistan.The United States abandoned its own germ 
program in 1969, and soonafter most of the world's nations signed an international 
treatybanning the development and possession of such weapons.The Soviet Union also 
signed the pact, but cheated on a massive scale,say former Soviet off!
ic!
ials who worked to refine the strains ofanthrax, among other germs, until the fall of 
the Soviet Union in1990.In the 1980's, other nations, notably Iraq, began developing 
the germas a weapon. Iraqi scientists spent more than five years on theproject, 
cultivating anthrax and processing it into a wet slurry thatwas loaded into bombs and 
missiles.United Nations inspectors who later studied the Iraqi program saidBaghdad did 
not manage to produce dry anthrax that could be deliveredas an aerosol though it did 
buy specialized nozzles for its fleet ofcrop- dusters.In the years since, United 
Nations officials say, Iraq has acquiredthe capability to produce the high-grade, dry 
anthrax of theappropriate particle size.None of this history gives investigators much 
of a hint as to theorigins of the current attack. It is not clear whether the 
anthraxsent to Senator Daschle was produced by the attacker or attackers,bought from a 
foreign nation or made with the help of a roguescientist.Nor w!
as!
 it known whether the attacker or attackers could make orobtain larger 
quantities.Former germ weapons scientists say that neither is easy. It tookexperienced 
Iraqi scientists several years to figure out how tocultivate large amounts of anthrax, 
which is the crucial first step tomaking a weapon.Drying the germs is relatively 
straightforward. But that processcreates a mix of particles that stick together, and 
most of them arefar too large for use as an effective weapon. Grinding the material 
toa small, uniform size without damaging a significant portion of thegerms is not 
easily done, former American and Soviet germ scientistssay.The discovery of expertly 
processed anthrax, one former scientistsaid, casts serious doubt on the theory 
advanced by some investigatorsthat the germ attacks were the work of a lone amateur 
with asmattering of knowledge about biology."I do think in one form or another, a 
state was involved," one formerAmerican scientist said. "It could be employees of !
a !
former state,such as a Russian scientist."Nor is it clear whether Al Qaeda, Osama bin 
Laden's network, wasinvolved in any way. American intelligence officials say Mr. bin 
Ladenhas tried to acquire nuclear, chemical and biological weapons.Until now, there 
has been no suggestion that he has succeeded in thisgoal, although there have been 
reports of testing chemicals and crudebiological weapons on animals at one of his 
training camps inAfghanistan.The attempted use of anthrax against a United States 
senator takesPresident Bush into a new, uncharted realm, particularly if the attackis 
ever linked to a specific nation. On the eve of the gulf war, hisfather weighed the 
question of whether to respond with nuclear weaponsto a germ attack against the United 
States-led coalition. After adiscussion among his senior advisers, President George 
Bush decidedagainst such retaliation. Instead, American officials sent Baghdad 
anambiguously phrased warning that was delivered in a letter from M!
r.!
Bush to Saddam Hussein."Your country," the letter said, "will pay a terrible price if 
youorder unconscionable acts."

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