Postdoctoral scientist positions are available at the Nathan Kline Institute 
(NKI) for Psychiatric Research 
(https://www.nki.rfmh.org<https://www.nki.rfmh.org/>) to work on computational 
neuroscience research funded by recently awarded NIH and DoD grants.


Our NIH-funded projects investigate the brain's dynamic circuit motifs 
underlying internal vs. external-oriented processes in the auditory and 
interconnected areas, using circuit modeling of the thalamocortical system. In 
this project, the postdoc will build data-driven biophysical models constrained 
by data collected from electrophysiology labs at NKI and Columbia (Noelle 
O’Connell, Charlie Schroeder, Dan Javitt) & The Feinstein Institutes for 
Medical Research (Stephan Bickel), and then use the models to predict optimal 
neuromodulation strategies for inducing/suppressing circuit patterns, testable 
in vivo. Related projects include investigating the origin of electrophysiology 
patterns observed in the auditory system of animal models of schizophrenia 
(biomarkers including mismatch negativity and altered oscillatory patterns), 
and using modeling to predict their circuit-level origins and potential 
treatments. Recent related publications 
(https://www.biorxiv.org/content/10.1101/2022.02.03.479036v2.abstract , 
https://www.eneuro.org/content/9/4/ENEURO.0281-21.2022.abstract , 
https://www.sciencedirect.com/science/article/pii/S0006322319318517).


Our DoD project involves developing computational models of the hippocampal and 
entorhinal cortex circuitry used in spatial navigation, higher level decision 
making circuits, and integrating the models with agents learning to solve 
navigation tasks using neurobiologically-inspired learning rules. This project 
includes mathematicians and robotics researchers at UTK and CMU. Recent related 
publications 
(https://www.frontiersin.org/articles/10.3389/fncom.2022.1017284/full , 
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0265808).


Applicants should have a strong background in: multiscale modeling using 
NEURON/NetPyNE, Python software development, neural/electrophysiology data 
analysis, machine learning, and writing/presenting research.


To apply, email a CV and cover letter to Sam Neymotin (samn...@gmail.com). The 
position requires presence at NKI (New York), with part telecommuting.



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