I had a quick look into nleiningen. I'm not able to bootstrap the build 
atm. Can't build the ClojureClrEx dep. What I basically did was:
git clone https://github.com/aaronc/nleiningen.git
git submodules init
git submodules update

nuget install Nuget.Core -o packages

$env:CLOJURE_LOAD_PATH="./src;./ClojureClrEx/src/;./ClojureClrEx"

created an init.clj with content and changed nleiningen.core/main to 
nleiningen.core/-main

init.clj:
(assembly-load-from 
"packages/Nuget.Core.2.2.0/lib/net40-Client/NuGet.Core.dll")

nleiningen.signing is missing from the sources. Just commented it out from 
nleiningen/core.clj

afterwards executed:
Clojure.Main.exe -i .\init.clj -m nleiningen.core repl

Mono.Cecil.dll
Loaded #<RuntimeAssembly Mono.Cecil, Version=0.9.5.0, Culture=neutral, 
PublicKeyToken=0738eb9f132ed756>
Mono.Cecil.Mdb.dll
Loaded #<RuntimeAssembly Mono.Cecil.Mdb, Version=0.9.5.0, Culture=neutral, 
PublicKeyToken=0738eb9f132ed756>
Mono.Cecil.Pdb.dll
Loaded #<RuntimeAssembly Mono.Cecil.Pdb, Version=0.9.5.0, Culture=neutral, 
PublicKeyToken=0738eb9f132ed756>
Mono.Cecil.Rocks.dll
Loaded #<RuntimeAssembly Mono.Cecil.Rocks, Version=0.9.5.0, 
Culture=neutral, PublicKeyToken=0738eb9f132ed756>
Trying to resolve ClojureClrEx
project.clj not found
Mono.Cecil.dll
Loaded #<RuntimeAssembly Mono.Cecil, Version=0.9.5.0, Culture=neutral, 
PublicKeyToken=0738eb9f132ed756>
Mono.Cecil.Mdb.dll
Loaded #<RuntimeAssembly Mono.Cecil.Mdb, Version=0.9.5.0, Culture=neutral, 
PublicKeyToken=0738eb9f132ed756>
Mono.Cecil.Pdb.dll
Loaded #<RuntimeAssembly Mono.Cecil.Pdb, Version=0.9.5.0, Culture=neutral, 
PublicKeyToken=0738eb9f132ed756>
Mono.Cecil.Rocks.dll
Loaded #<RuntimeAssembly Mono.Cecil.Rocks, Version=0.9.5.0, 
Culture=neutral, PublicKeyToken=0738eb9f132ed756>
Compile path: 
D:\Projects\Playground\clojure\test\clr\clode_org\nleiningen\bin
Error loading ClojureClrEx : #<NullReferenceException 
System.NullReferenceException: Object reference not set to an instance of 
an object.
   at clojure.lang.CljCompiler.Ast.GenContext..ctor(String sourceName, 
String assyName, String extension, String directory, Boolean 
createDynInitHelper) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\CljCompiler\Ast\GenContext.cs:line
 
105
   at 
clojure.lang.CljCompiler.Ast.GenContext.CreateWithExternalAssembly(String 
sourceName, String assyName, String extension, Boolean createDynInitHelper) 
in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\CljCompiler\Ast\GenContext.cs:line
 
86
   at 
clojure.lang.CljCompiler.Ast.GenContext.CreateWithExternalAssembly(String 
assyName, String extension, Boolean createDynInitHelper) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\CljCompiler\Ast\GenContext.cs:line
 
91
   at nleiningen/core$compile_project__1078.doInvoke(Object ) in eval:line 
233
   at clojure.lang.RestFn.invoke() in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\RestFn.cs:line 456
   at nleiningen/core$load_sub_project$fn__788__792.invoke() in eval:line 
152
   at nleiningen/core$load_sub_project__795.invoke(Object ) in eval:line 144
   at nleiningen/core$bootstrap_project$fn__826__830.invoke() in eval:line 
171>
Clojure 1.4.1

uncommented the local-dependencies in the project file, because 
ClojureClrEx doesn't have a project.clj, only a csproj. Therefore I added 
the ClojureClrEx to the load path

and now the repl works. but compile fails with

Compile path: 
D:\Projects\Playground\clojure\test\clr\clode_org\nleiningen\bin

Unhandled Exception: System.MissingMethodException: Cannot find member 
Compile matching args
   at CallSite.Target(Closure , CallSite , Object , Object , Object , 
Object , Object , Object )
   at CallSite.Target(Closure , CallSite , Object , Object , Object , 
Object , Object , Object )
   at 
nleiningen/core$compile_project$fn__959__963.__interop_Compile965(Object , 
Object __temp_1, Object __temp_2, Object __temp_3, Object __temp_4, Object 
__temp_5)
   at nleiningen/core$compile_project$fn__959__963.invoke() in eval:line 239
   at nleiningen/core$compile_project__1078.doInvoke(Object ) in eval:line 
238
   at clojure.lang.RestFn.invoke() in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\RestFn.cs:line 456
   at nleiningen/core$_main__1146.doInvoke(Object ) in eval:line 393
   at clojure.lang.RestFn.invoke(Object arg1) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\RestFn.cs:line 468
   at clojure.lang.Var.invoke(Object arg1) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\Var.cs:line 741
   at clojure.lang.AFn.ApplyToHelper(IFn fn, ISeq argList) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\AFn.cs:line 191
   at clojure.lang.Var.applyTo(ISeq arglist) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\Var.cs:line 874
   at clojure/core$apply__12458.invoke(Object , Object ) in core.clj:line 
601
   at clojure/main$main_opt__263.invoke(Object , Object ) in eval:line 343
   at clojure/main$main__338.doInvoke(Object ) in eval:line 446
   at clojure.lang.RestFn.invoke(Object arg1, Object arg2, Object arg3, 
Object arg4, Object arg5) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\RestFn.cs:line 586
   at clojure.lang.Var.invoke(Object arg1, Object arg2, Object arg3, Object 
arg4, Object arg5) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\Var.cs:line 761
   at clojure.lang.AFn.ApplyToHelper(IFn fn, ISeq argList) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\AFn.cs:line 208
   at clojure.lang.Var.applyTo(ISeq arglist) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure\Lib\Var.cs:line 874
   at Clojure.CljMain.Main(String[] args) in 
D:\work\clojure-clr-1.4.1-fix\Clojure\Clojure.Main\Main.cs:line 34

and I didn't figure out yet what the issue is.

Am Dienstag, 18. Dezember 2012 00:25:51 UTC+1 schrieb Aaron:
>
> Ok, sounds good.  I can do that.  I have 2-3 pretty specific changes that 
> I can outline.  I also have one bug fix (support for IntPtr and UIntPtr in 
> HostExpr).  Should I maybe start a separate thread in this group describing 
> the proposed changes or should we do this via JIRA or github?  I'm not 
> really sure whether the best method for doing this is git format-patch 
> (which generates a lot of patches) or some other method.
>
>
> On Mon, Dec 17, 2012 at 4:14 PM, dmiller <dmill...@gmail.com <javascript:>
> > wrote:
>
>> Aaron,
>>
>> tools.logging and nrepl are important.  I'm glad to see the effort.
>> I haven't forgotten about your single-DLL work.
>> I'm going to have plenty of time next week if you can get something to me.
>>
>> -David
>>
>>
>>
>> On Saturday, December 15, 2012 5:15:16 PM UTC-6, Aaron wrote:
>>>
>>> Cool.  I'm just seeing this now.  I actually spent some time a while 
>>> back getting a very simple nleiningen working in ClojureCLR.  I had nuget 
>>> downloads working and also the ability to AOT compile namespaces and merge 
>>> them into a single DLL.  It's not fully ready for prime time yet though, in 
>>> part because it depends on some custom modifications to the ClojureCLR 
>>> compiler.  In the long run, I'd like to work together on getting a full 
>>> lein clr implementation working.  I'd love to discuss further if you have 
>>> time.
>>>
>>> By the way Dave - speaking of custom modifications to ClojureCLR, this 
>>> past week, my colleague and I merged your latest master with our changes (
>>> https://github.com/**kocubinski/clojure-clr<https://github.com/kocubinski/clojure-clr>).
>>>  
>>>  I hope to put together some formal patches soon which clearly identify the 
>>> changes I'm suggesting for the main compiler.
>>>
>>> While we're at it, a few other things I'm working on or have working in 
>>> clojure-clr are:
>>> tools.logging and pinvoke 
>>> (https://github.com/aaronc/**ClojureClrEx<https://github.com/aaronc/ClojureClrEx>)
>>>  
>>> - logging is mostly ported but with only one backend working, 
>>> pinvoke/dllimport works great, but no docs
>>> a nice interface to WPF 
>>> (https://github.com/aaronc/**ClojureWpf<https://github.com/aaronc/ClojureWpf>)
>>>  
>>> - pretty stable, but again no docs yet
>>> nrepl 
>>> (https://github.com/aaronc/**tools.nrepl/tree/clr<https://github.com/aaronc/tools.nrepl/tree/clr>)
>>>  
>>> - needs quite a bit more work
>>>
>>> Unfortunately, I haven't been too diligent with documentation, but I 
>>> hope to correct that as time allows.  
>>>
>>> On Sunday, November 18, 2012 4:03:03 PM UTC-5, Shantanu Kumar wrote:
>>>>
>>>> Hi,
>>>>
>>>> I pushed lein-clr 0.2.0 
>>>> https://github.com/**kumarshantanu/lein-clr<https://github.com/kumarshantanu/lein-clr>
>>>>  JARs 
>>>> to Clojars a little while ago. The focus of this release is to
>>>>
>>>> 1. add dependency support (via NuGet/wget/curl, Leiningen :dependencies)
>>>> 2. lower the bar to get started with ClojureCLR (with automated 
>>>> download of ClojureCLR)
>>>> 3. remove the need to call `assembly-load-from` in code
>>>>
>>>> The changelog and TODO are here: https://github.com/**
>>>> kumarshantanu/lein-clr/blob/**master/CHANGES.md<https://github.com/kumarshantanu/lein-clr/blob/master/CHANGES.md>
>>>>
>>>> I hope this release is usable enough to start building ClojureCLR apps 
>>>> and libraries with it. This is an early project and can certainly use 
>>>> feedback and contribution. Please let me know what you think.
>>>>
>>>> Shantanu
>>>>
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