You are cordially invited to join  the Center for Biomolecular Structure 
Lecture Series ………..

Buz Barstow
Cornell University
www.vanderzanden-lab.com<https://urldefense.com/v3/__http://www.vanderzanden-lab.com/__;!!P4SdNyxKAPE!ER5XDnkeGcz1xOZOWZgkzZrW_IbypHVH5CMjhA-34KhMPjsUZccjZDUZtMrQ7Z1ti6P4yvCWsCaETU7VbC89FXyMlkrxrXbv-m8$>

WEDNESDAY, December 10, 13:30 (EST)

"The Microbe-Mineral Atlas and Biomining Critical Elements”

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Abstract: Creation of a new sustainable energy infrastructure, carbon 
sequestration, advanced electronic and computer technologies, and advanced 
defense technologies all mean that the demand for metals is increasingly 
rapidly. But traditional mining technology can be highly environmentally 
damaging. This means that the supply chains for many critical metals and 
semiconductors stretch through unstable parts of the world, leaving them 
vulnerable to disruption and exploitation.
     Biomining with Acidithiobacillus species already supplies about 20% of the 
world’s copper and 5% of its gold through an iron-specific redox process. 
However, there are no industrially-used microbes for any of the 30 or 40 other 
critical elements. This means that we will need to build microbes to enable 
bioprocesses to mine these elements with synthetic biology. However, we do not 
understand the basic science of how microbes interact with metals and minerals 
sufficiently to guide this engineering.
     My lab has characterized the genome of the mineral-dissolving microbe 
Gluconobacter oxydans and discovered the genetic systems that enable it to mine 
rare earth elements. We have used this new knowledge to create a roadmap for 
engineering G. oxydans that has already improved biomining of REE by up to 
1,200%. Furthermore, we engineered the hyper-engineerable microbe Vibrio 
natriegens to separate adjacent heavy lanthanides, leap-frogging solvent 
extractions.
     However, this still leaves over 20 other critical elements that we need 
build microbes for. To build the basic knowledge for this, my lab has started 
the Microbe-Mineral Atlas to catalog metal and mineral-interacting microbes 
from around the US, and hopefully the world.
     Finally, I will discuss some of the barriers that our current model of 
technology transfer poses to development of new technologies, what we have done 
to solve this problem, and some recent successes in starting REEgen for 
biomining rare earth elements, and Forage Evolution to develop 
hyper-engineerable microbes.


=================
Vivian Stojanoff, PhD
Education, Training, Outreach
User Program
p 1(631) 344 8375
e [email protected]<mailto:[email protected]>
w https://www.bnl.gov/ps/lifesciences/<https://www.bnl.gov/ps/lsbr/>

Address:
Center for Biomolecular Structure
National Synchrotron Light Source II
Building 745
Brookhaven National Laboratory
Upton NY 11973


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