Hello, As a workaround until XQuartz is fixed, you could try ChimeraX and ISOLDE for interactive model building and refinement. They do not depend on XQuartz.
https://www.cgl.ucsf.edu/chimerax https://tristanic.github.io/isolde If you get good performance on this computer, you might never even look back. I mostly work with cryoEM maps, but I know ISOLDE does live calculation of crystallographic maps (both 2Fo-Fc and Fo-Fc), which seems very convenient. If ISOLDE is too slow, there is a setting to lower simulation fidelity that will help make it run more smoothly (it doesn't affect the results much, since you would run a refinement program afterwards anyway). I hope this helps, Guillaume On 11/24/25 10:03 AM, Henry Man <[email protected]> wrote:
Hi, I have recently updated to MacOS 26.1, I can highly recommend that you do not for now. It has broken something with X11/XQuartz and therefore coot (0.9.8.96) is no longer launching. Others have bought up this issue with XQuartz github (https://github.com/XQuartz/XQuartz/issues/438). If anyone has any work arounds or fixes, would be very helpful to a coot-less crystallographer. Best Wishes, Henry Man ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/ VARNING: Klicka inte på länkar och öppna inte bilagor om du inte känner igen avsändaren och vet att innehållet är säkert. CAUTION: Do not click on links or open attachments unless you recognise the sender and know the content is safe.
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