Hi, I would try several runs of AlphaFold3 with different numbers of copies of the sequence, unless you have some specific information about expected interactions in the ring. If you’re lucky, it will give you a high confidence prediction for one of the trials.
Randy > On 6 Nov 2025, at 05:49, syed ibrahim > <[email protected]> wrote: > > Hi All > > I wnat to build a circular (ring) multimer with a 200 Å diameter from a > single monomer protein. Is there any program available? > I do not know the number of copies it may produce. > Thank you > Syed > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 ----- Randy J. Read Department of Haematology, University of Cambridge Cambridge Institute for Medical Research Tel: +44 1223 336500 The Keith Peters Building Hills Road E-mail: [email protected] Cambridge CB2 0XY, U.K. www-structmed.cimr.cam.ac.uk ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
