Dear colleagues,
*Two fully funded PhD positions *(under the BBSRC MIBTP DTP program) are available within the lab of Dr. Abhinav KV (https://www.akv-lab.com/) at the Department of Molecular and Cell Biology (MCB) and Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on membrane protein complexes involved in antimicrobial resistance (AMR) and phage therapy. The first one involves studying the molecular mechanism of horizontal gene transfer in bacteria while the second one involves studying defense mechanisms bacteria have evolved against bacteriophage infections. *Information for both these projects can be found here: * https://le.ac.uk/study/research-degrees/funded-opportunities/bbsrc-mibtp *About Us: * The AKV-lab (https://www.akv-lab.com/) is based at MCB and LISCB within University of Leicester (UoL), UK campus. The campus offers support for international students and a vibrant international network. For these interdisciplinary projects, we offer a vibrant interdisciplinary research environment and access to world-class research facilities for biochemistry, microbiology, biophysics, structural biology and cryo-EM. It welcomes candidates passionate about structural biology, protein structure-function, host-pathogen interactions, microbiology, phage-therapy and infectious diseases. You will learn molecular cloning, advanced membrane-protein purification techniques, *in-vitro* and *in-vivo* structural determination of multi-megadalton nanomachines using cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET). The projects utilize a multipronged approach involving techniques in biophysics, cross-linking mass-spectrometry, X-ray crystallography, integrative structural biology and live-cell imaging to address the scientific questions. Access to LISCB's X-ray facility and the cutting-edge microscopy infrastructure including state-of-the-art Titan Krios 300 keV microscope enhances this opportunity. We collaborate closely with members of the Division of Genetics, Genomics and Cancer Sciences (GGB), University of Leicester on these projects. *Eligibility: * · A Masters (M. Sc., M. S., M. Tech) or a Bachelors (B.Sc., B. S., B. Tech) degree in: Biochemistry, Molecular biology, Microbiology, Biotechnology, Bioinformatics or related disciplines · Acquired previous experience working in a wet lab and excellent command of written and spoken English. · Experience in recombinant protein expression/purification/structural biology (not required but preferable). · A strong motivation in pursuing biological questions and determination to actively contribute in establishing new research directions; strong interpersonal and teamwork skills. *Position details:* Both positions are funded for 4 years with a start date of August 2026. This position is open for both UK as well as international students. Successful candidates will be provided with a full tuition-fee waiver and an annual stipend for sustenance from BBSRC and University of Leicester, UK. The last date of application is *27th November 2025*. *How to apply: *Applicants will need to apply via the UoL website and more details on the application process can be found at: https://le.ac.uk/study/research-degrees/funded-opportunities/bbsrc-mibtp. You can also visit the* MIBTP website (* https://warwick.ac.uk/fac/cross_fac/mibtp/) for more details. To know more, visit our website: https://www.akv-lab.com/. We are based at the Leicester Institute of Structural and Chemical Biology, University of Leicester, UK: https://le.ac.uk/research/institutes/structural-chemical-biology. For informal enquiries, contact Dr. Abhinav KV, MCB & LISCB, University of Leicester: [email protected]. Please share this announcement within your institutions or forward it to anyone who might be interested. Regards, Abhinav. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
