Northwestern University seeks to recruit an enthusiastic and motivated 
cryo-electron microscopy (cryo-EM) Facility Manager to join the Structural 
Biology Facility (SBF), located on the Evanston campus. The successful 
applicant will be responsible for managing instrumentation and contributing to 
basic and translational research programs on both the Evanston and Chicago 
campuses. The SBF cryo-EM facility currently houses a TFS Glacios and JEOL 1400 
TEM. In addition, a new TFS Krios G4 will be installed in early 2025. The 
Glacios is equipped with a Selectrix energy filter and a Falcon 4i direct 
electron detector. Several instruments for sample preparation are also 
available as part of the SBF.

https://molbiosci.northwestern.edu/structural-biology-facility-manager-position/

Primary Responsibilities:

Train and assist users in negative stain and cryo-EM sample preparation, 
screening, and data collection
Contribute to the development and implementation of new EM experimental methods 
and protocols
Minimum qualifications:

Masters or Ph.D. degree with three years of hands-on cryo-EM experience in an 
EM laboratory.
Preferred qualifications:

Ph.D. degree in biochemistry, biology, chemistry, physics or related field
Experience in the use of TFS and JEOL microscopes and sample preparation
Experience with cryo-EM data collection software (SerialEM and/or EPU) and 
image processing software packages (Relion, Cryosparc, etc.)
Prior experience with different aspects of structural biology research, such as 
data collection, structure determination, model building, and refinement
Excellent technical, teaching, and verbal and written communication skills
Ability to work with others and as a team member
This position will report to the Facility Director. Salary commensurate with 
qualifications and experience.  Northwestern University provides excellent and 
competitive benefits.

Please submit your CV and ask for 2-3 reference letters to be directly sent to 
[email protected].  For full consideration, please submit your 
application by October 31, 2025.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of 
all protected classes. Women, racial and ethnic minorities, individuals with 
disabilities, and veterans are encouraged to apply.  Hiring is contingent upon 
eligibility to work in the United States.

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