Hi David,

Folddisco is a fantastic tool for motif search:

Structural motif search across the protein-universe with Folddisco
https://www.biorxiv.org/content/10.1101/2025.07.06.663357v1
https://search.foldseek.com/folddisco

Best wishes,
Tomas

On Wed, Sep 10, 2025 at 4:06 PM Sanders, David
<[email protected]> wrote:
>
> Hi all,
>
>
>
> We have recently determined the structure of a protein ligand complex, where 
> there is a Arg/carboxylate salt bridge,, where the plane of the Arg guanidino 
> group is perpendicular to the plane of the carboxyl group. I’m trying to find 
> other examples of the same orientation, but have had little luck (not even 
> fully sure how to do that search !). Does anyone have any examples of such an 
> interaction ?
>
>
>
> Many thanks for your help,
>
>
>
> David
>
>
>
> ------------------------------------------------------------------------------------
>
> Dr. David Sanders
>
> Department of Chemistry
>
> Professor of Structural Biology
>
> web page: https://research-groups.usask.ca/sanders/
>
> Email: [email protected]                  Ph : (306) 966-6788
>
>
>
> Mailing Address:                                                   Office : 
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>
> Department of Chemistry                                Lab : Thorv. 139
>
> University of Saskatchewan                           Lab Ph : (306) 966-1936
>
> 110 Science Place                                             Fax : (306) 
> 966-4730
>
> Saskatoon, SK, S7N 5C9, CANADA
>
>
>
>
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