Hi Gyuhyeok:

I think you might have to give disk access or file system access to X11 and/or 
coot  in MacOS System Preferences  > Security and Privacy > Privacy, i.e.,



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I’m stuck on an old version, but it should look somewhat similar.

HTH,

Bill

> On Apr 26, 2025, at 7:46 AM, 조규혁 <gyuhyeok...@gm.gist.ac.kr> wrote:
> 
> Dear all,
> 
> I recently upgraded to macOS 15.4.1 and cannot launch Coot via CCP4 
> Cloud-remote.
> 
> I installed XQuartz (ver 2.8.5, 2.8.3, or 2.8.0) and then CCP4 via the 
> Package Manager. Both CCP4i2 and the CCP4 Cloud interfaces (remote and local) 
> open normally, but clicking the CCP4 or Coot icons does nothing. The only way 
> I can run them is to open an XQuartz terminal and execute: ./ccp4i or ./coot. 
> Coot still will not open from within the CCP4 Cloud-remote interface.
> 
> Has anyone encountered and resolved this issue? Any advice to launch Coot 
> directly would be greatly appreciated.
> 
> Thank you in advance for your help.
> 
> Best regards,
> 
> Gyuhyeok
> 
> 
> Gyuhyeok Cho, Ph.D.
> Postdoctoral researcher
> Department of Chemistry
> Gwangju Institute of Science and Technology (GIST)
> 123 Cheomdangwagi-ro, Buk-gu, Gwangju, 61005
> Republic of Korea
> Tel. +82 62-715-4633
> e-mail: gyuhyeok...@gm.gist.ac.kr
> 
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1



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