Hi, We are starting an LCP crystallisation project with a client GPCR fusion protein soon.
Can anyone recommend a purchasable GPCR fusion protein that crystallises well in LCP and doesn't cost too much, that we can use as a positive control for the LCP setup process? Would also be good to hear community thoughts re the best screens to try (besides MemMeso) and any tips for optimizing LCP hits aside from simple grid screening. Thanks for your help, take care, Charlie. Charlie Nichols Research Leader | Structural Biology, Biophysics and Protein Science (SBBP) Small Molecule Drug Discovery | Charles River Chesterford Research Park, CB10 1XL, United Kingdom ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
