Dear all,
Structures of many large macromolecular assemblies are now being
determined using integrative approaches, wherein information derived
from multiple experimental and computational methods is combined to
compute their three-dimensional structures. PDB-IHM (formerly PDB-Dev)
is a system for archiving and disseminating structures determined using
integrative or hybrid methods (IHM), and making them Findable,
Accessible, Interoperable, and Reusable (FAIR).
In August 2024, PDB-Dev was unified with the PDB to deliver integrative
structures alongside experimental structures in thePDB archive
<https://files.wwpdb.org/pub/>. With unification, integrative structures
are assigned PDB accession codes and Digital Object Identifiers (DOIs),
annotated as IHM structures, and can be accessed from the PDB archive,
PDB DOI links (e.g., DOI:10.2210/pdb8zzc/pdb
<https://doi.org/10.2210/pdb8zzc/pdb>), and thePDB-IHM website
<https://pdb-ihm.org/>. Now part of the PDB infrastructure, PDB-Dev has
been rebranded as*PDB-IHM*, denoting IHM structures archived in the PDB.
Integrative structures can be deposited through thePDB-IHM deposition
portal <https://data.pdb-ihm.org/>and accessible from thewwPDB OneDep
home page <https://deposit.wwpdb.org/>. They are processed in parallel
to thewwPDB OneDep system <https://deposit.wwpdb.org/>. Structures
processed by PDB-IHM are released synchronously with PDB structures
weekly on Wednesdays at 00:00 UTC.
In the future, the wwPDB partners, including Research Collaboratory for
Structural Bioinformatics Protein Data Bank (RCSB PDB
<https://rcsb.org/>) in the United States, Protein Data Bank in Europe
(PDBe <https://ebi.ac.uk/pdbe/>), and Protein Data Bank Japan (PDBj
<https://pdbj.org/>), will disseminate integrative structures on their
respective websites.
We look forward to supporting the structural biology community with
depositing integrative structures toPDB-IHM <https://pdb-ihm.org/>.
Questions or feedback?
Contactdeposit-help@mail.wwpdb.orgorheld...@pdb-ihm.org.
Kind regards,
Deborah Harrus, on behalf of the wwPDB
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Deborah Harrus, Ph.D.
PDBe Archive Project Leader, Biocuration Lead
PDBe - Protein Data Bank in Europe
European Bioinformatics Institute (EMBL-EBI)
European Molecular Biology Laboratory
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD UK
http://www.PDBe.org
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