Hi Jiazhi,

I found that ccp4i2 worked after deleting my local Python3.9 library and before 
re-installing Xquartz.

Thank you for bringing Xquartz to my attention; I had overlooked that it needed 
to be replaced, too.

Best regards,

Blaine
________________________________
From: Tang, Jiazhi <jiazhi.tang...@alumni.ucl.ac.uk>
Sent: Friday, January 10, 2025 8:16 AM
To: Mooers, Blaine H.M. (HSC) <blaine-moo...@ouhsc.edu>; CCP4BB@JISCMAIL.AC.UK 
<CCP4BB@JISCMAIL.AC.UK>
Subject: [EXTERNAL] Re: [ccp4bb] Issues with MacOS 15.2

Dear all,

Thanks all for your generous suggestions. It turns out install XQuarts and 
grants it full access perfectly solved the issue.

Again, appreciate your kind suggestions!

Regards,
Jiazhi

Sent from Outlook for 
iOS<https://urldefense.com/v3/__https://aka.ms/o0ukef__;!!GNU8KkXDZlD12Q!-bmWXuuceXgOyJWsj4bRUzMb9O9RQFXKloUEYeZabPG82RrAtfT5Nnw8zxXMKXMzRczwudOohRBcQh_sC-QCFRj9UYk5gpjU3zDc1Q$>
________________________________
From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Mooers, Blaine 
H.M. (HSC) <blaine-moo...@ouhsc.edu>
Sent: Friday, January 10, 2025 2:09:34 PM
To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK>
Subject: Re: [ccp4bb] Issues with MacOS 15.2

Hi Jiazhi,

Thank you for the post.
I, too, have a new m4 Mac with OS 15.2 Sequoia.
I had installed ccp4-9 two days ago, but only checked that mtzdump ran in the 
terminal (it did).
I had not checked ccp4i.

I can confirm some trouble similar to yours.
Some of my troubles were created by transferring code from my old Intel Mac and 
are not the fault of the CCP4 developers.

I cannot fire up ccp4i in the terminal by entering ccp4i.
However, I can run `mtzdump` and `acorn` in the terminal.
This is strange because they also reside in /Applications/ccp4-9.0/ccp4-9/bin 
with ccp4i.
I can fire up the ccp4i GUI by entering the full path in the terminal: 
/Applications/ccp4-9.0/ccp4-9/bin/ccp4i.
By terminal, I mean iterm2.

With ccp4i2, which was recognized in my terminal, it tries to tap into my local 
library of Pyton3.9 code (in ~/Library/Python/3.9).
It tries to import some Cython libraries from my six-year-old Intel chip Mac.
I need to delete Python3.9 library and reinstall Python3.9 with home brew or 
macports.

I noticed that I also have Python3.9 in anaconda.
I had  transferred anaconda from my Intel Mac
I need to delete anaconda, reinstall anaconda, and rebuild the envs.

This is the bottom of the error message that I received when trying to start 
ccp4i2:

ImportError: 
dlopen(/Users/blaine/Library/Python/3.9/lib/python/site-packages/_cffi_backend.cpython-39-darwin.so,
 0x0002): tried: 
'/Users/blaine/Library/Python/3.9/lib/python/site-packages/_cffi_backend.cpython-39-darwin.so'
 (mach-o file, but is an incompatible architecture (have 'x86_64', need 
'arm64e' or 'arm64')), 
'/System/Volumes/Preboot/Cryptexes/OS/Users/blaine/Library/Python/3.9/lib/python/site-packages/_cffi_backend.cpython-39-darwin.so'
 (no such file), 
'/Users/blaine/Library/Python/3.9/lib/python/site-packages/_cffi_backend.cpython-39-darwin.so'
 (mach-o file, but is an incompatible architecture (have 'x86_64', need 
'arm64e' or 'arm64'))

Best regards,

Blaine

Blaine Mooers, Ph.D.
Associate Professor
Department of Biochemistry and Physiology
College of Medicine
University of Oklahoma Health Sciences
S.L. Young Biomedical Research Center, Rm. 466
975 NE 10th 
Street<https://urldefense.com/v3/__https://maps.google.com/?q=975*NE*10th*Street&entry=gmail&source=g__;Kysr!!GNU8KkXDZlD12Q!-bmWXuuceXgOyJWsj4bRUzMb9O9RQFXKloUEYeZabPG82RrAtfT5Nnw8zxXMKXMzRczwudOohRBcQh_sC-QCFRj9UYk5gpj6EuasOw$>,
 BRC 466
Oklahoma City, OK 73104-5419

Central Time Zone (follows Daylight Savings Time)

office: (405) 271-8300   lab: (405) 271-8313

________________________________
From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Arnaud Basle 
<0000b39969b3d1dc-dmarc-requ...@jiscmail.ac.uk>
Sent: Friday, January 10, 2025 6:42 AM
To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK>
Subject: [EXTERNAL] Re: [ccp4bb] Issues with MacOS 15.2

Hi Jiazhi,

Good luck with you new adventures!

You may want to contact specifically the CCP4 core team and they should be able 
to help.

They may not have seen you email on the ccp4BB as we were at the study weekend 
the past 3 days.

You can contact me off list if you don't manage to get a contact with CCP4 team.

Cheers,
Arnaud


On 09/01/2025 17:19, Tang, Jiazhi wrote:

⚠ External sender. Take care when opening links or attachments. Do not provide 
your login details.

Dear all,

I got a new working computer based on apple M4 pro chip and OS 15.2 Sequoia. 
But when I tried to download newest ccp4 version and run it, it doesn't work. 
Ccp4, ccp4 cloud local and ccp4i2 all can not be oponed. Does anyone know how 
to access this issue?

Really appreciate any generous help!

Regards,
Jiazhi Tang


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