Dear all,

A Post-doctoral fellowship is available in our team. See details below.

Best regards,

Laurent


An ANR-funded post-doctoral position is available in the “Structural Biology of Bacterial Macromolecular Complexes” team at Molecular Microbiology and Structural Biochemistry Laboratory (MMSB, UMR 5086). The group is hosted at the Institute of Biology and Protein Chemistry (IBCP, Lyon) and enjoys a very dynamic and collaborative atmosphere. Our research aimed at deciphering the structural basis of key events of Gram-negative bacteria infection process. Our expertise lies in the study of macromolecular complexes by integrative structural biology: X-ray crystallography, small angle X-ray scattering, cryo-EM, PPI, etc..

The position aims at investigating the molecular determinants and dynamics of the interaction between Type VI secretion system (T6SS) components to understand how the late stages of the assembly of nanomachine are controlled. The project is funded by the French ANR Agency (ANR CO-6TER), with a national consortium which involved five institutes: LISM in Aix Marseille, MMSB in Lyon, IECB in University of Bordeaux, BIP in Aix Marseille and Institute Pasteur in Paris. It will be important to note that a part of experiments will be performed at IECB (Bordeaux) so the candidate is expected to spend significant amount of time there. The candidate should hold a PhD in Structural Biology. He/she should have strong experience in purifying protein and protein complexes, perform protein-protein interaction studies. Knowledge in cryo-EM and/or bacterial secretion systems would be an asset.

The postdoc will work closely with Dr. Priscillia Lagoutte and Dr. Esther Marza, who will provide tailored mentorship throughout the research process, offering expertise in PPI, biochemistry and cryo-EM studies.

 The application must include: CV, Motivation Letter and Reference letters addressed to Dr. *Priscillia Lagoutte* priscillia.lagou...@univ-lyon1.fr. Before the 27 November 2024 Expected start date: February/March 2025 (some flexibility depending on the candidate’s availability) Salary based on national grids (CNRS)

--
Laurent Terradot
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Director of Research CNRS
Principal Investigator

lab web 
page:http://perso.ibcp.fr/laurent.terradot/terradot_lab/Terradot_Lab.html

Structural Biology of Bacterial Macromolecular Complexes
Institut de Biologie et Chimie des Protéines,
UMR 5086 CNRS-Université Lyon 1
7 passage du vercors, 69007 Lyon Cedex, France
Cell Phone +33(0)6 33 69 73 14
Phone +33(0)4 72 72 26 52
Fax +33(0)4 72 72 26 04
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