Hello all,


The annual SSRL/LCLS Users’ Meeting at SLAC National Accelerator Laboratory 
will be held from September 22-27, 2024.



The Metals in Structural Biology Workshop is scheduled for Friday Sept 27 from 
8:30am-5pm Pacific Time (Agenda below).  2024 will be the seventh year the 
workshop is running during the SSRL/LCLS User’s Meeting.  We have had some 
fantastic interactions in the last few years.  Our goal is to continue to bring 
together a group of people to speak on various aspects of studying metals in 
biology using synchrotron, XFEL, cryo-EM, and neutron sources, as well as to 
discuss future goals and needs.



Registration for the full SSRL/LCLS Users Meeting is still open (registration 
link: https://tinyurl.com/yc6mp8ps). There are a lot of amazing sessions at 
this year’s meeting!



If you are unable to attend in person, we have set up a Zoom session (Zoom 
registration link: https://tinyurl.com/5e57krpk).  Note the zoom link is for 
the Metals in Structural Biology Workshop only.



Please join us if you are interested!

Warmly,

Sarah and Jennifer

Metals in Structural Biology Workshop Agenda (Pacific Time)

8:30 AM Intro - Jennifer Bridwell-Rabb, University of Michigan & Sarah Bowman, 
Hauptman-Woodward Institute/University at Buffalo  (organizers)

9:00 AM Organometallic Masquerade at the heart of Wood-Ljungdahl: strides 
toward the CO intermediate of carbon monoxide dehydrogenase - Macon Abernathy, 
SLAC National Accelerator Laboratory

9:30 AM Elucidating diatomic selectivity in the heme-dependent, carbon 
monoxide-sensing transcription factor PxRcoM-1 - Matt Dent, Wayne State 
University

10:00 AM Coffee Break

10:30 AM Elucidating Ligand Interactions and Small-Molecule Activation of a 
Heme Enzyme in Pyrrolnitrin Biosynthesis - Yifan Wang, University of Georgia

11:00 AM New Roles for Manganese in Biology - Jon Rittle, UC Berkeley

11:30 AM Spectroscopic and computational studies of a unique S = 7/2 [Fe4S4]+ 
cluster and its functional role in Ferredoxin:Thioredoxin Reductase from 
Methanogenic Archaea - Alex Guo, Carnegie Mellon University

1:00 PM Panel with panelists Graham George, U Saskatchewan, Aimin Liu, The 
University of Texas at San Antonio, Alliena Maggiolo, SLAC National Accelerator 
Laboratory, Steve Ragsdale, University of Michigan

2:30 PM Identification and localisation of light metal ions by long-wavelength 
crystallography - Armin Wagner, Diamond Light Source

3:00 AM Coffee Break

3:30 PM Neutron crystallographic studies of metalloenzymes: application to 
lytic polysaccharide monooxygenases - Flora Meilleur, NC State University and 
Oak Ridge National Laboratory

4:00 PM A Role for Histidine in NiSOD Maturation - Michael Maroney, University 
of Massachusetts

4:30 PM The role of metal ions in the structure and function of alkane 
monooxygenase (AlkB) - Rachel Austin, Barnard College

5:00 PM End

Sarah EJ Bowman PhD
Associate Investigator | Hauptman-Woodward Medical Research Institute
Director | National Crystallization Center | Hauptman-Woodward Medical Research 
Institute
Research Associate Professor | Department of Biochemistry and Department of 
Structural Biology |
University at Buffalo | Jacobs School of Medicine and Biomedical Sciences

Member | US National Committee for Crystallography
Fellow | American Crystallographic Association – The Structural Science Society

p: +1 716 898 8623
e1: sbowman at hwi.buffalo.edu
e2: sebowman at buffalo.edu

Research Webpage<https://hwi.buffalo.edu/scientist-directory/sbowman/>
Crystallization Center Webpage<http://www.getacrystal.org>

Hauptman-Woodward Medical Research Institute
700 Ellicott Street | Buffalo, NY 14203

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