Hi Muneer, You can try the 3D Proteome Viewer at Coronavirus3d.org https://coronavirus3d.org/#/3dproteomeviewer
Use Google Chrome as does not work well in other browsers. On the link, hover over and click Nsp6 Scroll down and you will see all mutations in Nsp6 mapped to the alphafold model and a list of all mutations back to 2020 with the frequency. You can export the data as a .cvs file to sort as you choose. The data are automatically updated once a month. There is lots of other good data on this site so look around. Here is the publication on this database (https://pubmed.ncbi.nlm.nih.gov/32470119/) When I find a specific mutation I am interested in, I use Nextstrain.org and label the tree by genotype to colorize on the lineage map. https://nextstrain.org/ncov/gisaid/global/6m You will need to translate the nsp6 mutation location to the exact position on Orf1A as nsp1-11 are a single protein on nextstrain. Nextstrain is now mapping mpox and other emerging infections so useful also in the future. Good luck. Karla Satchell From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Muneer Ahmad <ahmedmunir122...@gmail.com> Date: Wednesday, September 4, 2024 at 10:45 PM To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK> Subject: Re: [ccp4bb] Job opportunities at SARomics Biostructures Dear All, I'm hoping someone can assist me with accessing or searching for data related to Sara CoV 2 variants. Specifically, I'm interested in the NSP6 protein and would like to identify variants that have been found in different species. If anyone has recommendations for databases, repositories, or specific search terms, I would be very grateful. Thank you, Muneer Ahmad On Thu, Sep 5, 2024, 1:24 AM Derek Logan <0000ac2332bb2871-dmarc-requ...@jiscmail.ac.uk<mailto:0000ac2332bb2871-dmarc-requ...@jiscmail.ac.uk>> wrote: Dear all, Just a reminder that job opportunities are available at SARomics Biostructures in Lund, Sweden, a rapidly growing CRO in structural biology for the pharma and biotech sectors. SARomics are looking to recruit several scientists in protein expression and purification, as well as crystallography, to join their highly international team. The company is in an exciting expansion phase and just moved into brand new tailor-made labs at the lively life science hub Medicon Village a couple of weeks ago. See here for more details of the positions: Positions at SARomics Biostructures<https://urldefense.com/v3/__https:/www.saromics.com/about/career/__;!!Dq0X2DkFhyF93HkjWTBQKhk!VmUSnTrQ3B0_jBcVYuS1XKe6teuIssjdqVk9UhM6b5DLofcqm21CRz54EHv3YfVbslD78KTTJoPpJkW6-DaoFQYAj_f37R1ka_s$> saromics.com<https://urldefense.com/v3/__https:/www.saromics.com/about/career/__;!!Dq0X2DkFhyF93HkjWTBQKhk!VmUSnTrQ3B0_jBcVYuS1XKe6teuIssjdqVk9UhM6b5DLofcqm21CRz54EHv3YfVbslD78KTTJoPpJkW6-DaoFQYAj_f37R1ka_s$> [cid:C90C84C1-7FE5-476A-9FDE-E310050B5327]<https://urldefense.com/v3/__https:/www.saromics.com/about/career/__;!!Dq0X2DkFhyF93HkjWTBQKhk!VmUSnTrQ3B0_jBcVYuS1XKe6teuIssjdqVk9UhM6b5DLofcqm21CRz54EHv3YfVbslD78KTTJoPpJkW6-DaoFQYAj_f37R1ka_s$> The deadline is 9th September. Please note, as before, the requirement to be already legally entitled to work in Sweden. /Derek _____________________________________________________ Derek Logan Professor | Biochemistry and Structural Biology Centre for Molecular Protein Science Lund University, Box 124, 221 00 Lund, Sweden www.cmps.lu.se<https://urldefense.com/v3/__http:/www.cmps.lu.se__;!!Dq0X2DkFhyF93HkjWTBQKhk!VmUSnTrQ3B0_jBcVYuS1XKe6teuIssjdqVk9UhM6b5DLofcqm21CRz54EHv3YfVbslD78KTTJoPpJkW6-DaoFQYAj_f3lnPtyHY$> ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1<https://urldefense.com/v3/__https:/www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1__;!!Dq0X2DkFhyF93HkjWTBQKhk!VmUSnTrQ3B0_jBcVYuS1XKe6teuIssjdqVk9UhM6b5DLofcqm21CRz54EHv3YfVbslD78KTTJoPpJkW6-DaoFQYAj_f3JOgDieE$> ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1<https://urldefense.com/v3/__https:/www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1__;!!Dq0X2DkFhyF93HkjWTBQKhk!VmUSnTrQ3B0_jBcVYuS1XKe6teuIssjdqVk9UhM6b5DLofcqm21CRz54EHv3YfVbslD78KTTJoPpJkW6-DaoFQYAj_f3JOgDieE$> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
