Dear Kyle,

I often like lookint at the crystal.idx file [1] for PDB structures
with very similar cell dimensions ... and then doing some quick MR to
see if one of those sticks out. Easy to fully automate if you have a
local copy of the PDB archive, but something like that (bash)

  cell="30 40 50 90 90 90" # your cell
  maxd=2                   # max deviation (A and degree)
  [ ! -f crystal.idx ] && wget -q 
https://files.wwpdb.org/pub/pdb/derived_data/index/crystal.idx
  awk -v cell="$cell" -v maxd=$maxd 'BEGIN{
    i=split(cell,c)
  }
  /CRYST1/{
    for(i=1;i<=6;i++) {
      d=c[i]-$(i+2);if(d<0)d=-d
      if(d>maxd)next
    }
    print
  }' crystal.idx

would give you a first listing ...

Cheers

Clemens

[1] https://files.wwpdb.org/pub/pdb/derived_data/index/crystal.idx


On Wed, Jul 03, 2024 at 03:54:20PM +0000, Kyle Gregory wrote:
> Dear all,
> 
> We have a unit cell that is too small for our expected protein and suspect we 
> have crystalised a contaminant.
> 
> Does anyone have any recommendations on which tools we could use to identify 
> the possible contaminant? I've tried SIMAD on ccp4cloud and it doesn't 
> suggest anything reasonable.
> 
> Kind regards,
> Kyle
> 
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*--------------------------------------------------------------
* Clemens Vonrhein, Ph.D.     vonrhein AT GlobalPhasing DOT com
* Global Phasing Ltd., Sheraton House, Castle Park 
* Cambridge CB3 0AX, UK                   www.globalphasing.com
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