Do Nature do embarrassment?

H

> On 14 May 2024, at 10:54, Frank von Delft 
> <0000bcb385fe5582-dmarc-requ...@jiscmail.ac.uk> wrote:
> 
> What we really need is a tweet from Nature, declaring their embarrassment at 
> having been suckered into becoming DeepMind's advertising arm.  
> 
> 
> On 14/05/2024 01:56, Paul Adams wrote:
>> 
>> The letter may have had (or helped have) an impact already:
>> 
>> On X today from Pushmeet Kohli @ DeepMind
>> 
>> "We love the excitement & results from the community on AlphaFold 3 and are 
>> doubling the AF Server daily job limit to 20. Happy to also share that we're 
>> working on releasing the AF3 model (incl weights) for academic use, which 
>> doesn’t depend on our research infra, within 6 months".
>> 
>> 
>>> On May 13, 2024, at 11:11 AM, Wankowicz, Stephanie 
>>> <0000d0e1738c7100-dmarc-requ...@jiscmail.ac.uk> wrote:
>>> 
>>> If it does what it claims – incredibly impressive. The issue we have is 
>>> there is no way to verify or validate the claims it is making. 
>>> 
>>> The letter is a call and start of a conversation about how the 
>>> ever-changing landscape of communication and publication of science should 
>>> be.
>>> 
>>> -Stephanie Wankowicz
>>> From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Krieger, 
>>> James M <krieg...@pitt.edu>
>>> Sent: Monday, May 13, 2024 10:22 AM
>>> To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK>
>>> Subject: Re: [ccp4bb] Fwd: AlphaFold3 Transparency and Reproducibility
>>>  
>>> This Message Is From an External Sender 
>>> This message came from outside your organization. 
>>> It definitely is impressive but it also has clear limitations
>>> 
>>>> On 13 May 2024, at 15:22, Sylvia Fanucchi 
>>>> <0000d0c4e77ae410-dmarc-requ...@jiscmail.ac.uk> wrote:
>>>> 
>>>> 
>>>> 
>>>> You don't often get email from 
>>>> 0000d0c4e77ae410-dmarc-requ...@jiscmail.ac.uk. Learn why this is important
>>>> 
>>>> Is it just me who is really impressed by it? Am I missing something?
>>>> 
>>>> Get Outlook for Android
>>>> From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Rafael 
>>>> Marques <rafael_mmsi...@hotmail.com>
>>>> Sent: Monday, May 13, 2024 3:13:16 PM
>>>> To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK>
>>>> Subject: Re: [ccp4bb] Fwd: AlphaFold3 Transparency and Reproducibility
>>>>  
>>>> I tried it yesterday and I was really shocked by how fast it is. When I 
>>>> was preparing to submit my second job, the first one was already finished, 
>>>> which made me think that I was definitely doing something wrong. Probably 
>>>> I was...
>>>> 
>>>> Best wishes 
>>>> 
>>>> Rafael Marques 
>>>> 
>>>> 
>>>> On 13 May 2024 09:53, Harry Powell 
>>>> <0000193323b1e616-dmarc-requ...@jiscmail.ac.uk> wrote:
>>>> Hi folks 
>>>> 
>>>> This arrived in my inbox this morning, and I believe that it may provoke 
>>>> some discussion…
>>>> 
>>>> Wikipedia tells me: στέργει γὰρ οὐδεὶς ἄγγελον κακῶν ἐπῶν 
>>>> 
>>>> Best wishes! 
>>>> 
>>>> Harry 
>>>> 
>>>> >    From: Stephanie Wankowicz <mullane.stepha...@gmail.com> 
>>>> >    Sent: Saturday, May 11, 2024 3:31 PM 
>>>> >    To: James Fraser <jaimefra...@gmail.com>; Pedro Beltrao 
>>>> > <pedrobelt...@gmail.com>; Benjamin Cravatt <crav...@scripps.edu>; Roland 
>>>> > Dunbrack <roland.dunbr...@gmail.com>; Anthony Gitter 
>>>> > <git...@biostat.wisc.edu>; Kresten Lindorff-Larsen <lindo...@bio.ku.dk>; 
>>>> > Sergey Ovchinnikov <s...@mit.edu>; Polizzi, Nicholas F. 
>>>> > <nicholasf_poli...@dfci.harvard.edu>; Brian Shoichet 
>>>> > <bshoic...@gmail.com>
>>>> >    Subject: AlphaFold3 Transparency and Reproducibility 
>>>> > 
>>>> > 
>>>> >    This email from mullane.stepha...@gmail.com originates from outside 
>>>> > Imperial. Do not click on links and attachments unless you recognise the 
>>>> > sender. If you trust the sender, add them to your safe senders list 
>>>> > <https://spam.ic.ac.uk/SpamConsole/Senders.aspx> to disable email 
>>>> > stamping for this address. 
>>>> > 
>>>> >    Hello, 
>>>> > 
>>>> > 
>>>> >    As many of you, we were incredibly disappointed with the lack of code 
>>>> > or even executables accompanying the publication of AlphaFold3 in 
>>>> > Nature. AlphaFold3 was released without the means to test and use the 
>>>> > software in a high-throughput manner. This does not align with the 
>>>> > principles of scientific research, which rely on the ability of the 
>>>> > community to evaluate, use, and build upon existing work.
>>>> > 
>>>> > 
>>>> > 
>>>> >    We have written a letter, which will be posted on Zenodo and 
>>>> > submitted as a Letter to the Editor in the coming days.
>>>> > 
>>>> > 
>>>> > 
>>>> >    Please see the entire letter here. 
>>>> > <https://docs.google.com/forms/d/e/1FAIpQLSf6ioZPbxiDZy5h4qxo-bHa0XOTOxEYHObht0SX8EgwfPHY_g/viewform?usp=sf_link>
>>>> >  If you want to endorse this letter, please fill out your name, 
>>>> > affiliation, and email in the form.
>>>> > 
>>>> > 
>>>> > 
>>>> >    Additionally, a PDF version of the letter can be found here 
>>>> > <https://drive.google.com/file/d/1u1D3KzsllpI_6I0drA9RdIiENd9EK1Hz/view?usp=sharing>.
>>>> > 
>>>> > 
>>>> > 
>>>> >    Thank you, 
>>>> > 
>>>> > 
>>>> > 
>>>> >    Stephanie Wankowicz, UCSF 
>>>> > 
>>>> >    Pedro Beltrao, ETH 
>>>> >    Benjamin Cravatt, Scripps 
>>>> >    Roland Dunbrack, FCCC 
>>>> >    Anthony Gitter, UW Madison 
>>>> >    Kresten Lindorff-Larsen, Copenhagen 
>>>> >    Sergey Ovchinnikov, MIT 
>>>> >    Nicholas Polizzi, DFCI/HMS 
>>>> >    Brian Shoichet, UCSF 
>>>> >    James Fraser, UCSF 
>>>> > 
>>>> > 
>>>> 
>>>> ######################################################################## 
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>> 
>> --
>> Paul Adams (he/him/his)
>> Associate Laboratory Director for Biosciences, LBL 
>> (https://biosciences.lbl.gov) 
>> Principal Investigator, Computational Crystallography Initiative, LBL 
>> (http://cci.lbl.gov) 
>> Vice President for Technology, the Joint BioEnergy Institute 
>> (http://www.jbei.org) 
>> Principal Investigator, ALS-ENABLE, Advanced Light Source 
>> (http://als-enable.lbl.gov) 
>> Laboratory Research Manager, ENIGMA Science Focus Area 
>> (http://enigma.lbl.gov) 
>> Adjunct Professor, Department of Bioengineering, UC Berkeley 
>> (http://bioeng.berkeley.edu) 
>> Member of the Graduate Group in Comparative Biochemistry, UC Berkeley 
>> (http://compbiochem.berkeley.edu) 
>> 
>> Building 91, Room 410
>> Building 978, Room 4126
>> Tel: 1-510-486-4225
>> http://cci.lbl.gov/paul 
>> ORCID: 0000-0001-9333-8219
>> 
>> Lawrence Berkeley Laboratory
>> 1 Cyclotron Road
>> BLDG 91R0183
>> Berkeley, CA 94720, USA.
>> 
>> Executive Assistant: Michael Espinosa [ meespin...@lbl.gov ][ 1-510-333-6788 
>> ]
>> Phenix Consortium: Ashley Dawn [ ashleyd...@lbl.gov ][ 1-510-486-5455 ]
>> --
>> 
>> 
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> 
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