Dear All
I have been using coot as part of my normal workflow but since last week I have 
been having issues with Coot after I built my own PC which contains the 
following Hardware:
CPU - AMD Ryzen 9 5950X 16-Core Processor - 16 Cores, 32 Threads
RAM - 64 GB
GPU - AMD Radeon RX 6600 XT - Primary/Discrete
GPU VRAM - 8176 MB - GDDR6 2000 MHz

Despite the improvement in hardware, Coot is now having issues refining 
molecules when using the 'real space refine' tool and other related tools. When 
trying to refine, the program becomes stuttering and slow such that it becomes 
unfeasible to use the program in a reasonable amount of time. My current work 
around is to run Coot through CCP4 cloud but this greatly slows down my 
workflow. From what I can see Coot is not be optimised for the AMD CPU.

Any help or would be greatly appreciated.

Kind regards,
Otsile

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