Dear All,


I am excited to let you know that the Arimura Lab (launched in February 2024 in 
Basic Sciences Division, Fred Hutch Cancer Center, Seattle, WA, USA) is looking 
for a Postdoctoral Fellow to help establish an inclusive, diverse, innovative, 
and collaborative research team.



The successful candidate must have a keen interest in chromatin biology and the 
courage to develop novel approaches. We are particularly interested in 
combining structural biology and genomics approaches.



The mission of the Arimura Lab is to elucidate the regulation mechanisms of 
biological events occurring in eukaryotic chromosomes. Our Lab will accomplish 
this elucidation by developing novel approaches. The lab currently possesses 
unique technology to determine the high-resolution cryo-EM structures of 
chromatin-related complexes isolated from interphase and M phase chromosomes 
formed in Xenopus (frog) egg extract (PMID: 34478647) and Magnetic Isolation 
and Concentration (MagIC)-cryo-EM, a technique enabling direct structural 
analysis of targets captured on nanomagnetic beads, which allows for the 
structural determination of scarce macromolecules (< 0.0005 mg/mL) in 
heterogeneous samples (PMID: 38328033 [preprint]).


The fellow will either work on implementing our unique technologies or further 
advancing them (e.g. combining them with genomics, applying these technologies 
to tissue culture cells) to elucidate the structural basis of the biological 
events occurring in eukaryotic chromosomes, such as the transcription 
regulation in euchromatin and heterochromatin, the mitosis-specific mechanisms 
that compact chromosomes and assemble kinetochores, and the accessible 
chromatin formation around transcription start site.


The Arimura Lab provides a supportive environment that strongly emphasizes 
individualized mentoring. Upon joining, we will prioritize your continued 
development as an independent scientist. We will collaborate with you to 
identify and develop plans to achieve your research and professional 
development goals. In addition, Fred Hutch and the Basic Sciences Division 
offer numerous career development opportunities, benefits, and competitive 
salaries (starting at approximately $68k, with scheduled raises to ~$91k by 
2027) for postdoctoral fellows.

Please visit the following link to learn more and apply.
https://careers-fhcrc.icims.com/jobs/27135/post-doctoral-research-fellow---arimura-lab/job

Best Regards,
Yasu Arimura

yarim...@fredhutch.org<mailto:yarim...@fredhutch.org>
Assistant Professor, Basic Sciences Division
Fred Hutchinson Cancer Center
1100 Fairview Ave N,
Seattle, WA 98109


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