From: Polina Isaikina and Gebhard FX Schertler

PhD Position Available in the Schertler Lab at the Paul Scherrer Institute with 
 Polina Isaikina (Switzerland)

In the BIO Division at the Paul Scherrer Institute we have an exceptional 
opportunity for a PhD student to join our team specializing in modern 
structural biology of membrane proteins. The project will focus on the 
structural and functional elucidation of light-activated GPCRs from 
invertebrates, with an additional aspect involving GPCR engineering for 
optogenetic applications. The successful candidate will have the opportunity to 
enrol at ETH in the Life Science Zürich Graduate School. The position will be 
open starting from January 2024.

For more information, please refer to the following papers from our research 
group:

Varma et al. "Crystal Structure of Jumping Spider Rhodopsin-1 as a 
Light-Sensitive GPCR." PNAS, 2019.

Isaikina et al. "Structural basis of the activation of the CC chemokine 
receptor 5 by a chemokine agonist.” Science
Advances, 2021.

Gruhl et al. "Ultrafast Structural Changes Direct the First Molecular Events of 
Vision." Nature, 2023.

We look forward to welcoming a motivated and enthusiastic candidate to 
contribute to groundbreaking research in the field of structural biology of 
membrane proteins.

How to apply:
Applicants should submit a CV, a motivation letter and two contact details for 
reference letters to
Polina Isaikina polina.isaik...@psi.ch and Gebhard Schertler 
gebhard.schert...@psi.ch


Prof. em. Gebhard F.X. Schertler ETH
ERC Investigator

Head of Biology and Chemistry
Department
Paul Scherrer Institut
Laboratory of Biomolecular Research,
LBR
OFLC 109
CH-5232 Villigen PSI
gebhard.schert...@psi.ch
phone +41 (0)56 310 4265
http://bio.web.psi.ch


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