A postdoctoral position is available in the Kory lab at the Harvard T.H. Chan School of Public Health to investigate the biochemical mechanisms of mitochondrial metabolite transport.
We are looking for highly motivated individuals with a background in in vitro biochemistry, structural biology and/or biophysics to join our multi-disciplinary international team. The strong focus on molecular and mechanistic research in metabolism, and age-related diseases in the Department of Molecular Metabolism and the general excellence of biomedical research in the area provide an ideal environment for postdoctoral training with relevance to human health and disease. *https://www.hsph.harvard.edu/molecular-metabolism/* <https://www.hsph.harvard.edu/molecular-metabolism/> Research in the Kory lab focuses on the role of organelles in metabolic compartmentalization and regulation. Our current work centers on mitochondria, critical organelles in metabolism generating both energy and precursors for biosynthesis. Beyond their metabolic roles, mitochondria are being recognized as important signaling hubs and mitochondrial dysfunction has been associated with major diseases including cancer, diabetes, and neurodegeneration. The Kory lab takes multi-faceted approaches including biochemistry, structural biology, functional genomics, metabolite profiling, imaging and mouse models to determine how mitochondria achieve efficient metabolite exchange and conversion while maintaining the unique chemical environment of the mitochondrial matrix. Ultimately, we hope our research in understanding mitochondrial metabolite transport in humans will contribute to progress in the treatment of diseases with deregulated metabolism such as cancer and diabetes. For more information, please visit: *https://kory-lab.com/* <https://kory-lab.com/> The ideal candidate has a strong background in in vitro biochemistry, structure biology and/or biophysics and experience in methods and technologies such as protein expression and purification, thermostability assays, in vitro reconstitution, activity and binding assays, methods for protein structure determination, cross-linking mass spectrometry, and will join ongoing efforts in developing and applying systematic approaches to transporter identification and characterization. Please contact Dr. Nora Kory (nk...@hsph.harvard.edu) with your CV, a cover outlining your past research experience and your motivation for joining the lab, as well as contact information for 2-3 references. Qualifications: *Basic Qualifications* - Ph.D. in biochemistry, biological sciences, biophysics, or a related field - Motivation to understand metabolite transport, biology and disease at a mechanistic - Excellent communication, writing, and organizational skills - In-depth biochemistry/structural biology/biophysics experience *Additional**l**Qualifications* AdditionallQualificationslorlExpertiselinlanyloflthelfollowinglareaslisl valued: • Metabolomics, proteomics, mass spectrometry • Microfluidics • Microscopy ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
