A postdoctoral fellow position is available at the Xiao lab, Department of 
Pathology, Case Western Reserve University (CWRU, since 1826) in Cleveland, 
Ohio, for a highly motivated individual to study the molecular mechanisms of 
the inflammasome signaling pathways and the downstream events of cytokine 
secretion and gasdermin-mediated pyroptosis. We use structural, biochemical and 
cellular approaches to dissect the molecular details of protein-protein, and 
protein-ligand interactions. 
For more information, please see:
https://case.edu/medicine/pathology/research/pathology-labs/xiao-lab
https://www.ncbi.nlm.nih.gov/myncbi/tsan.xiao.1/bibliography/public/?page=1

Qualifications
We are seeking future career scientists capable of independent thinking and 
interested in learning new techniques. The ideal candidate must have a M.D. or 
Ph.D. degree with less than five years of postdoctoral experience. Strong 
skills in protein expression, purification and molecular biology are essential. 
Knowledge in structural biology approaches such as cryo-EM or X-ray 
crystallography is desirable. The candidate must possess excellent written and 
oral communication skills, and will be expected to work in a diverse and 
collaborative environment. 

Salary will follow NIH guidelines and commensurate with experience.
Please e-mail your CV and a brief description of research experience and 
interests, plus three reference letters to: t...@case.edu

CWRU School of Medicine is ranked #25 in medical research in the US 
(https://www.usnews.com/best-graduate-schools/top-medical-schools/research-rankings).
 CWRU is located in University Circle in Cleveland, Ohio, a hub for art, 
culture, and sports with a low cost of living and outstanding schools. 
University Circle houses the world-famous Cleveland Orchestra, the Cleveland 
Museum of Art, the Cleveland Museum of Natural History and the Crawford 
Auto-Aviation Museum. Cleveland is home to Major League baseball, football and 
basketball teams and is surrounded by a ring of parks and Lake Erie, ideal 
locations for hiking, sailing and other outdoor activities. Cleveland is home 
to the Rock and Roll Hall of Fame, a stunning lakeshore building designed by 
I.M. Pei (https://www.thisiscleveland.com/).
Tsan Sam Xiao, Ph.D.
Professor, Department of Pathology
Case Western Reserve University
Wolstein Research Building, Room 6533 (office), 6317 (lab)
2103 Cornell Road, Cleveland, OH 44106-7288
U.S.A.
Phone: 216-368-3330 (office)
FAX: 216-368-0494
E-mail: t...@case.edu


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