PhD student in Single Molecule Biophysics / Structural & Molecular Biology
The Rudolf Virchow Center / Research Center for Integrative and
Translational Bioimaging of the University of Würzburg has a vacancy
for a
PHD STUDENT
IN THE FIELD OF SINGLE MOLECULE AND STRUCTURAL STUDIES OF DNA REPAIR
AND TRANSCRIPTION REGULATION
Applications are invited for an exciting PhD opportunity at the
interface between single molecule biophysics, structural as well as
cellular studies. The project addresses tumour-associated interactions
between DNA repair processes and gene transcription.
Our laboratory studies the molecular mechanisms of different DNA
repair protein systems using single molecule approaches. We use atomic
force microscopy (AFM) imaging and single molecule fluorescence
microscopy coupled optical tweezers, as well as a range of biochemical
and biophysical functional assays, to obtain synergistic information
on diverse mechanisms of DNA repair systems. In addition, we are
interested in the intriguing interplay between DNA repair proteins and
DNA replication on the one hand, and gene transcription on the other
hand. The PhD project will exploit a combination of single molecule,
crystallographic, and cellular approaches for the characterisation of
protein interactions in DNA repair and transcription regulation.
The Rudolf Virchow Center and the University of Würzburg offer state
of the art infrastructure and provide a highly motivating scientific
environment. Successful PhD applicants will have the opportunity to
enroll in an international graduate program at the Graduate School of
Life Sciences (GSLS) in Würzburg. The University also provides various
support, for example with moving to Würzburg through the International
Office and the Welcome Centre.
To apply, you should hold a Master degree in biophysics, biochemistry,
or a related field and be enthusiastic about mechanistic aspects of
protein systems in DNA processing. Ideally, you have a background in
single molecule biophysics and/or structural biology. The positions
are available immediately and come with a competitive salary based on
Public Service of German Federal States TV-L (E13).
Please send applications (including cover letter, CV, copies of
certificates, and contact information for two referees) as a single
pdf file (no more than 10 MB) to
ingrid.tess...@virchow.uni-wuerzburg.de until 1 JUNE 2023. The
University of Würzburg is an equal opportunity employer.
_ _ _ _ _ _ _ _ _ _ _ _ _ _ _
Ingrid Tessmer, PhD, PD
University of Würzburg
Rudolf Virchow Center
Josef Schneider Str. 2 (D15)
97080 Würzburg
Germany
Tel. +49 (0)931 - 31 80 425
email ingrid.tess...@virchow.uni-wuerzburg.de
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