Dear All,

I am unsure if all other groups will get it - but I am sure this group will 
understand the frustration.

My NIH grant did not get funded.  A few genuine comments - they make excellent 
sense.  We will fix that.

One major comment is, “Structures can be predicted by alpfafold and other 
software accurately, so the effort put on the grant to get structures by X-ray 
crystallography/cryo-EM is not justified.”

The problem is when a company with billions of $$s develops a method and blasts 
it everywhere - the message is so pervasive…

Question: Is there a canned consensus paragraph that one can add with 
references to grants with structural biology (especially if the review group is 
not a structural biology group) to say why the most modern structure prediction 
programs are not a substitute for structural work?

Thanks.


Rams
subra...@purdue.edu




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