Applications from highly qualified candidates are invited for postdoctoral positions in my lab at the University of South Alabama in Mobile, AL. There are several NIH-funded projects: One is an ongoing project to elucidate molecular mechanisms underpinning the cephalosporin resistance of Neisseria gonorrhoeae conferred by mutated penicillin-binding protein 2 (PBP2). Another is a structure/function analysis of PlzA, a cyclic-di-GMP binding protein from the Lyme disease spirochete, Borreliella burgdorferi, to understand its biological roles in the enzootic cycle of the pathogen. Finally, there is a project to develop a lead compound against familial hypercholesterolemia.
Projects entail site-directed mutagenesis, cloning, purification and crystallization of proteins, collecting diffraction data, solving structures by X-ray crystallography, and various biophysical techniques (ITC, fluorescence spectroscopy). Investigations using cryo-EM are also planned. Qualifications: Candidates should hold a PhD in biochemistry or chemistry, with a strong background in molecular biology and protein crystallography. For the PBP2 project, experience with enzyme kinetics is preferred. To apply: Please send cover letter and CV directly to me by email to <mailto:cdav...@southalabama.edu> cdav...@southalabama.edu. Informal enquiries by email are welcome. Christopher Davies, Ph.D. Professor, Dept. of Biochemistry & Molecular Biology 5795 USA Drive N, CSAB 234 University of South Alabama Mobile AL 36688 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
