Job opening for a postdoctoral position to join the Structural Motility team at 
the Curie Institute Paris, France.



The Structural Motility team is searching for a post-doctoral fellow to join a 
dynamic laboratory directed by Anne Houdusse at the Curie Institute (Paris 
Center).

    We are looking for an expert in biophysics/biochemistry and structural 
determination to gain insights on how drugs in phase 3 clinical trials operate 
for novel therapies against cardiac diseases.  The position will also lead to 
the development of chemical biology tools. Our team indeed innovate to 
investigate and understand molecular mechanisms in cells. By joining our team, 
the post-doctoral fellow will also join efforts on determination of structures 
by cryoEM and will increase his/her knowledge on the cytoskeletal by functional 
and cellular studies.



Our team studies the mechanism and function of force production by molecular 
motors and has made important discoveries on how force generation can power 
cellular processes in human health and how mutations in their function lead to 
disease.  A multi-disciplinary approach that combines structural biology (x-ray 
and cryoEM), chemical biology and cell biology is being used in our studies.  
With such an approach, we decipher how molecular motors produce force by 
visualizing yet unknown structures, or by understanding how their activity is 
regulated. We use chemical biology and cell biology approaches to test insights 
from structures.  We also investigate and develop specific modulators of the 
force generated by these motors (including compounds in phase 3 clinical 
trials) to investigate how force modulation can lead to new therapies.



We are looking to recruit and train a dynamic and motivated candidate who can 
quickly gain independence and take the lead on one of our exciting scientific 
projects.  Experience in cryo-electron microscopy or cell biology is a plus.



If you are interested, please send a CV and a statement of research interests 
and goals as well as three letters of recommendation from your previous 
employers.
Contact : Anne Houdusse (anne.houdu...@curie.fr<mailto:anne.houdu...@curie.fr>)
Website : Structural Motility Team https://institut-curie.org/team/houdusse


Anne Houdusse-Juillé
Directeur de Recherche CNRS
Institut Curie
Head of the Structural Motility Laboratory
Cell Biology & Cancer
CNRS UMR144
26, Rue d'Ulm 75248 - Paris Cedex 05
TEL. +33 (0)1 56 24 63 95
https://curie.fr/personne/anne-houdusse-juille
https://institut-curie.org/team/houdusse
https://institut-curie.org/popin/team-anne-houdusse?destination=science_org/80


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