Dear CCP4bb-ers, We are readvertising this postdoctoral post at beamline VMXi, Diamond Light Source and I would be very grateful if you could pass it on to potentially suitable candidates. This post would potentially suit somebody within a physics or computer science department as well as in chemistry or life sciences, so I will be particularly appreciative if it could be passed on to colleagues in those fields.
The closing date is 22nd of May this year, there is a link at the end for applications and also candidates should feel free to get in touch informally for a chat. Thanks, Mike 3 year Postdoctoral scientist position at Diamond Light Source Closing date: 22nd of May 2022 Crystal structures derived from X-ray diffraction have been central to our understanding of the function of proteins essential to life and critical in the development of new medicines including those for Covid 19. Recently the importance of determining these structures at near-physiological or room temperatures rather than under cryo-cooled conditions has become apparent. However, a major challenge is that only partial datasets are obtained at room temperature and the best means to combine many of these partial datasets into a complete dataset and present the results to the end user have not yet been established. Notable challenges faced by multi-crystal data processing include identification of a consensus symmetry, and automated identification of the optimal subset(s) of data to use for downstream analysis, accounting for the potential presence of non-isomorphism and radiation damage. We are seeking to recruit an enthusiastic scientist to develop novel algorithms, software tools and statistical techniques for the analysis of multi-crystal X-ray diffraction data sets. The appointed person will work closely with experimental scientists in the development of new and existing software to improve the quality of automated feedback provided to experimental users. The successful candidate will likely have experience in: * Statistical analysis of data * Algorithm and software development. * Numerical and scientific computing with Python Knowledge of x-ray diffraction data analysis would be beneficial for applicants but is not a requirement. Full details of the vacancy and application procedure may be found here: https://vacancies.diamond.ac.uk/vacancy/postdoctoral-research-associate-vmxi-468465.html for informal enquiries contact: michael.ho...@diamond.ac.uk<mailto:michael.ho...@diamond.ac.uk> or richard.gil...@diamond.ac.uk<mailto:richard.gil...@diamond.ac.uk> Prof Mike Hough Principal Beamline Scientist - VMXi Diamond Light Source Ltd Harwell Science and Innovation Campus -- This e-mail and any attachments may contain confidential, copyright and or privileged material, and are for the use of the intended addressee only. If you are not the intended addressee or an authorised recipient of the addressee please notify us of receipt by returning the e-mail and do not use, copy, retain, distribute or disclose the information in or attached to the e-mail. Any opinions expressed within this e-mail are those of the individual and not necessarily of Diamond Light Source Ltd. Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments are free from viruses and we cannot accept liability for any damage which you may sustain as a result of software viruses which may be transmitted in or with the message. Diamond Light Source Limited (company no. 4375679). Registered in England and Wales with its registered office at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
