Dear colleagues, We are looking for a GPCR structural biologist to come and join our team in Molecular Pharmacology. Please see job description that follows. Please don't send me your CV, but rather apply on-line via the provided link. Thank you! -Dirk
https://lilly.wd5.myworkdayjobs.com/LLY/job/US-San-Diego-CA/Advisor-GPCR-Structural-Biologist_R-30223 ---Job Description Follows--- At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. The Discovery Chemistry & Technologies organization within Lilly Research Laboratories is a dynamic group seeking a highly skilled scientist to join our structural biology team. We support drug discovery for numerous innovative projects and are looking for qualified scientists for structural biology efforts of challenging drug discovery targets including GPCRs and membrane proteins. This role is located at our Lilly Biotechnology Center in San Diego, CA. Do you have experience leading and collaborating in a team environment? We are a diverse team of scientists that strive for excellence and innovative solutions to find therapies for our patients. Join our team today and make a difference using your structural biology knowledge and expertise! Join the Lilly Family today! Responsibilities: * Employ innovative technologies to advance structural biology activities for GPCRs and protein complexes to drive SBDD efforts. Broad experience with membrane proteins, along with a proven track record of structural determination is required. * Drive structure determination and drug design for multiple challenging GPCR and membrane protein targets, as well as soluble protein targets * Apply pioneering biochemical, biophysical, and computational approaches to accelerate generation of high-quality reagents for crystallization and CryoEM studies * Determine structures and co-structures of novel protein targets and analyze pertinent data for the rational design of both small-molecule and antibody therapeutics * Provide structure-based drug design leadership and support by multiple methods for a broad range of targets across different therapeutic areas * Partner closely with other structural biologists, biophysicists, protein biochemists and medicinal chemists to develop integrative approaches and address specific project needs and challenges * Collaborate on multidisciplinary teams designing novel therapeutics, presenting scientific data in support of drug discovery projects Basic Requirements: Ph.D. in Structural Biology, Biophysics, Biochemistry, Chemistry or other relevant field with applicable training or experience in the field of structural biology. Additional Preferences: * Experience in both X-ray crystallography and cryo-EM * Experience in structure-based drug design * Comprehensive knowledge of GPCR biology and pharmacology * Prior industry experience and a strong publication record highly preferred * Flexibility to work in an environment with evolving priorities and completion timelines, with strong interpersonal, written & verbal communication, and problem-solving skills * Strong capability to collaborate with scientists in multiple fields and to mentor staff scientists in drug discovery; experience leading teams focusing on structural biology efforts * Familiarity with other biophysical methods (E.g., MS, bioNMR, SPR, BLI, etc.) would be helpful Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( lilly_recruiting_complia...@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law). Dirksen Bussiere, Ph.D., M.B.A. Assoc. Vice President/Head, Molecular Pharmacology (Quantitative and Structural Biology) Lilly Research Laboratories Eli Lilly and Company Lilly Biotechnology Center Phone: 510-759-7013 10290 Campus Point Dr. E-mail: bussiere_dirk...@lilly.com<mailto:bussiere_dirk...@lilly.com> San Diego, CA 92121 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
