We are looking for senior postdoctoral researchers to join an exciting structure-based drug design project funded by the Bill&Melinda Gates foundation in the Sayers' laboratory to develop inhibitors of a Plasmodium nuclease involved in DNA replication. These posts have arisen from a successful feasibility study also funded by the foundation. For background on the nuclease and our work in this area click here <http://www.sayers.staff.shef.ac.uk/fen/index.html>.
One post requires a PDRA with proven experience in protein structure determination by NMR. The application documents for this post can be found here. here. <https://tinyurl.com/2p9aahsc> Documents for the second post (which requires a PDRA with experience in X-ray crystallography ) will be released shortly. This Sheffield University-based project is supported by extensive Medicinal Chemistry, ADME/PK and parasite testing resources from worldwide collaborators arranged by the foundation and represents a truly exciting opportunity to be involved in the fight against malaria. The posts are for up to 16 months in the first instance. The posts are both time sensitive meaning that candidates able to commence quickly will be at an advantage. You will join a group of three other PDRAs working on this project and an MCIF fellow working on a related program in Trypanosomes. The NMR work will be carried out in Prof. Jon Waltho's lab and crystallography is supervised by Dr Pat Baker (both Sheffield). The posts are both based in Sheffield, UK. Depending on experience, we are able to appoint at or near the top end of the scale advertised. Feel free to contact me to discuss. -- Professor Jon R Sayers, FRSB Department of Infection, Immunity & Cardiovascular Disease University of Sheffield Medical School Beech Hill Rd Sheffield S10 2RX United Kingdom Tel: +44 (0)114 215 9552 Fax: +44 (0)114 271 1863 Email: j.r.say...@sheffield.ac.uk https://www.sheffield.ac.uk/iicd/profiles/sayers <http://www.sheffield.ac.uk/iicd/profiles/sayers> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
